tRNA derived fragment (tRF)-3009 participates in modulation of IFN-α-induced CD4+ T cell oxidative phosphorylation in lupus patients

Abstract Background Accumulating evidence suggests tRNA-derived fragments (tRFs) play important roles in cellular homeostasis. Here we aimed to explore aberrant expression of tRFs in CD4+ T cells from patients with systemic lupus erythematosus (SLE) and their potential function in the SLE pathogenes...

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Bibliographic Details
Published in:	Journal of Translational Medicine
Main Authors:	Guannan Geng, Huijing Wang, Weiwei Xin, Zhe Liu, Jie Chen, Zhang Danting, Fei Han, Shuang Ye
Format:	Article
Language:	English
Published:	BMC 2021-07-01
Subjects:	tRNA derived fragments (tRFs) Systemic lupus erythematosus (SLE) CD4+ T cells Oxidative phosphorylation (OXPHOS) Type I interferon (IFN)
Online Access:	https://doi.org/10.1186/s12967-021-02967-3

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