| Summary: | The demand for naturally derived cosmetic ingredients is rising as consumers increasingly prioritize green and environmentally friendly products. Naturally derived ingredients, such as plant extracts rich in polyphenols like flavonoids and tannins, are often perceived as more sustainable and beneficial for skincare. <i>Epilobium angustifolium</i> (fireweed) is a circumpolar plant with traditional uses in Northern and Eastern Europe known for its skincare benefits. This review explores the chemical composition, traditional uses, and potential skincare benefits of <i>E. angustifolium</i>, focusing on its anti-inflammatory and antioxidant properties. Literature surveys, ethnopharmacological research, and database searches were conducted to investigate the properties of <i>E. angustifolium</i>. The plant contains various compounds such as flavonoids, phenolic acids, tannins, steroids, and triterpenes, each with potential skincare benefits. Pharmacological reports suggest that <i>E. angustifolium</i> exhibits antioxidant and antibacterial properties, making it a valuable ingredient in skincare products. The availability of <i>E. angustifolium</i> in the market as a raw material for cosmetics offers opportunities for formulators to create innovative products with skin-conditioning and anti-inflammatory properties. Understanding the chemical composition and bioactivity of <i>E. angustifolium</i> can guide the development of effective and sustainable skincare formulations.
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