Design, Preparation, and Evaluation of Osthol Poly-Butyl-Cyanoacrylate Nanoparticles with Improved In Vitro Anticancer Activity in Neuroblastoma Treatment

Osthol (osthole), known as a neuroprotective drug, has shown potent anticancer activity. However, the potential clinical application of osthol is limited due to its low water solubility and low bioavailability. Polybutyl cyanoacrylate (PBCA) has been widely used to improve the solubility of drugs wi...

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Bibliographic Details
Published in:	Molecules
Main Authors:	Liqing Zheng, Lixia Shen, Ze Li, Xiaoli Zhang, Miaomiao Wu, Yuanyuan Zhang, Jianhua Liu
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Subjects:	osthol SH-SY5Y endocytosis PBCA nanoparticle neuroblastoma
Online Access:	https://www.mdpi.com/1420-3049/27/20/6908

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