Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells.

The proteasome inhibitor bortezomib represents an important advance in the treatment of multiple myeloma (MM). Bortezomib inhibits the activity of the 26S proteasome and induces cell death in a variety of tumor cells; however, the mechanism of cytotoxicity is not well understood. We investigated the...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS ONE
المؤلفون الرئيسيون: Feng Ge, Chuan-Le Xiao, Li-Jun Bi, Sheng-Ce Tao, Sheng Xiong, Xin-Feng Yin, Li-Ping Li, Chun-Hua Lu, Hai-Tao Jia, Qing-Yu He
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Public Library of Science (PLoS) 2010-09-01
الوصول للمادة أونلاين:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20927383/?tool=EBI