Acute granulomatous interstitial nephritis and ulcerative colitis: a case report and literature review

Tubulo-interstitial nephritis (TIN) in patients affected by inflammatory bowel disease, both ulcerative colitis and Crohn’s disease, is usually considered as drug-associated to aminosalicylate. We report a rare case of granulomatous active tubulo-interstitial nephritis in a young patient with a rece...

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Bibliographic Details
Published in:Italian Journal of Medicine
Main Authors: Giorgia Comai, Olga Baraldi, Vania Cuna, Valeria Corradetti, Maria Cappuccilli, Marco Busutti, Deborah Malvi, Benedetta Fabbrizio, Massimo Campieri, Gaetano La Manna
Format: Article
Language:English
Published: PAGEPress Publications 2018-03-01
Subjects:
Aminosalicylate therapy
inflammatory bowel disease
tubulo-interstitial nephritis
steroid therapy.
Online Access:http://www.italjmed.org/index.php/ijm/article/view/929
Description
Summary:Tubulo-interstitial nephritis (TIN) in patients affected by inflammatory bowel disease, both ulcerative colitis and Crohn’s disease, is usually considered as drug-associated to aminosalicylate. We report a rare case of granulomatous active tubulo-interstitial nephritis in a young patient with a recent diagnosis of ulcerative colitis naïve to aminosalicylate treatment. The patient has been successfully treated with steroids administration. Our purpose is to sensitize that TIN should always to be considered in differential diagnosis an extra-intestinal manifestation of bowel disease.
ISSN:1877-9344
1877-9352

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