Investigation of adenosine A1 receptor-mediated β-arrestin 2 recruitment using a split-luciferase assay

Background: Adenosine A1 receptor (A1AR) plays a prominent role in neurological and cardiac diseases and inflammatory processes. Its endogenous ligand adenosine is known to be one of the key players in the sleep–wake cycle. Like other G protein-coupled receptors (GPCRs), stimulation of A1AR leads to...

書誌詳細
出版年:	Frontiers in Pharmacology
主要な著者:	Luisa Saecker, Hanns Häberlein, Sebastian Franken
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2023-05-01
主題:	adenosine A1 receptor β-arrestin 2 cAMP nanoluciferase live cell assay valerian
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1172551/full

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