Screening marker genes of type 2 diabetes mellitus in mouse lacrimal gland by LASSO regression

Abstract Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance and a relative deficiency of insulin. This study aims to screen T2DM-related maker genes in the mouse extraorbital lacrimal gland (ELG) by LASSO regression.C57BLKS/J strain with leptin db/db homozygous mice (T2DM, n = 20...

Full description

Bibliographic Details
Published in:	Scientific Reports
Main Authors:	Xiaoting Pei, Di Qi, Jiangman Liu, Hongli Si, Shenzhen Huang, Sen Zou, Dingli Lu, Zhijie Li
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-04-01
Online Access:	https://doi.org/10.1038/s41598-023-34072-4

Similar Items

Circadian disruption and ROS-NLRP3 signaling mediate sleep deprivation-enhanced silica nanoparticle toxicity in lacrimal glands
by: Wenxiao Zhang, et al.
Published: (2025-09-01)

A Ligation of the Lacrimal Excretory Duct in Mouse Induces Lacrimal Gland Inflammation with Proliferative Cells
by: Ying Liu, et al.
Published: (2017-01-01)

Lacrimal gland tumours
by: Dhir S, et al.
Published: (1985-01-01)

Lacrimal gland myxoma
by: Drushti Parikh, et al.
Published: (2017-01-01)

Amyloidosis of lacrimal gland
by: Prabhakaran Venkatesh, et al.
Published: (2009-01-01)

Amyloidosis of lacrimal gland
by: Kumar Vinod, et al.
Published: (2010-01-01)

Morphological features of the porcine lacrimal gland and its compatibility for human lacrimal gland xenografting.
by: Robert Henker, et al.
Published: (2013-01-01)

Primary Lymphoma of the Lacrimal Gland on PET/CT Imaging
by: Ahmet Şen, et al.
Published: (2024-09-01)

Metastatic Osteosarcoma of Lacrimal Gland
by: Smitha K Shambhu, et al.
Published: (2017-07-01)

Lacrimal gland involvement in sarcoidosis
by: H Yanardag, et al.
Published: (2003-07-01)

Bilateral Lacrimal Gland Lymphoma
by: Namrata, et al.
Published: (2018-07-01)

Mixed Tumour of the Lacrimal Gland
by: Reddy Bhaskara, et al.
Published: (1955-01-01)

Mucoepidermoid tumour of lacrimal gland
by: Gandhewar R, et al.
Published: (1977-01-01)

Mixed tumours of the lacrimal gland
by: Das S
Published: (1961-01-01)

Traumatic prolapse of the lacrimal gland
by: Nahata M, et al.
Published: (1973-01-01)

Mixed tumour of lacrimal gland
by: Kulkarni R, et al.
Published: (1977-01-01)

Ectopic lacrimal gland in the eyelids
by: Kaushik Nikhil
Published: (1985-01-01)

Congenital lacrimal gland cutaneous fistula with ectopic lacrimal gland: case report and literature review
by: DONG Bingran, et al.
Published: (2025-01-01)

The impact of lacrimal gland characteristics on the clinical presentation of lacrimal gland prolapse in candidates for upper eyelid blepharoplasty
by: Bahram Eshraghi, et al.
Published: (2025-03-01)

PPARγ: the dominant regulator among PPARs in dry eye lacrimal gland and diabetic lacrimal gland
by: Peng-Yue Mu, et al.
Published: (2020-06-01)

Bilateral Primary Lacrimal Gland Lymphoma
by: Kürşad Ramazan Zor, et al.
Published: (2016-12-01)

Adenoid Cystic Carcinoma of the Lacrimal Gland
by: Celine Chaaya, et al.
Published: (2024-10-01)

Advances in clinical examination of lacrimal gland
by: Yuan Lin, et al.
Published: (2023-08-01)

Lacrimal Gland Amyloidosis in an Elderly Patient
by: Toshiya Nagai, et al.
Published: (2020-03-01)

Unusual presentation of lacrimal gland tumours
by: Singh J, et al.
Published: (1992-01-01)

Plexiform Neurofibroma Involving the Lacrimal Gland
by: Mikael Hofsli, et al.
Published: (2017-01-01)

Lacrimal gland adenoma in a sheep
by: G. Farjanikish, et al.
Published: (2019-03-01)

Primary epithelial tumour of the lacrimal gland
by: Consul B, et al.
Published: (1961-01-01)

A protocol for immunostaining of macrophages in whole-mount mouse cornea, conjunctiva, and lacrimal gland
by: Saleh Alfuraih, et al.
Published: (2024-12-01)

Screening of potential markers for vitiligo based on bioinformatics and LASSO regression and prediction of Chinese medicine
by: Wei Liang, et al.
Published: (2025-06-01)

Evaluation of the Efficacy of Immune and Inflammatory Markers in the Diagnosis of Lacrimal-Gland Benign Lymphoepithelial Lesion
by: Fuxiao Luan, et al.
Published: (2023-03-01)

Pleomorphic Adenoma of an Ectopic Lacrimal Gland in the Eyebrow
by: Gurvinder Kaur, et al.
Published: (2011-07-01)

Lacrimal Gland, Ocular Surface, and Dry Eye
by: Chuanqing Ding, et al.
Published: (2016-01-01)

Recurrence of Primary Synovial Sarcoma of the Lacrimal Gland
by: Abhijeet Yadav, et al.
Published: (2015-01-01)

Lacrimal gland enlargement in acute myeloid leukemia
by: Ajaz N Koul, et al.
Published: (2013-01-01)

Bilateral Lacrimal Gland Lymphoma in Sjögren Syndrome
by: Melis Palamar, et al.
Published: (2016-01-01)

Clinical Analysis of Castleman’s Disease of the Lacrimal Gland
by: Dongping Li, et al.
Published: (2020-01-01)

Unusual Presentation of Lacrimal Gland Pleomorphic Adenoma
by: Shailesh Mani Pokharel, et al.
Published: (2014-09-01)

Tattoo-associated lacrimal gland enlargement and sarcoidosis
by: Amritha Devi Kanakamedala, et al.
Published: (2023-12-01)

Lacrimal Gland Abscess: A Case Report
by: Mayari Ito, et al.
Published: (2023-12-01)