The macroscopic and microscopic effects of imidazolium ionic liquids on blood and their interactions with serum albumins

Ionic liquids (ILs) begin to be applied in more broad scopes and even in medicine steadily, so it is very necessary to study their biocompatibility, bioactivity, and influence on blood. For the first time, the main effects of popular imidazolium ILs with common anions and alkylated cations on rabbit...

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Bibliographic Details
Published in:Green Chemistry Letters and Reviews
Main Authors: Qing He, Xu Peng, Wanhang Jiang, Sara Toufouki, Shun Yao
Format: Article
Language:English
Published: Taylor & Francis Group 2022-07-01
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Online Access:https://www.tandfonline.com/doi/10.1080/17518253.2022.2102439
Description
Summary:Ionic liquids (ILs) begin to be applied in more broad scopes and even in medicine steadily, so it is very necessary to study their biocompatibility, bioactivity, and influence on blood. For the first time, the main effects of popular imidazolium ILs with common anions and alkylated cations on rabbit blood were explored and compared comprehensively. A series of key indices and characteristic methods were applied in this systematic study. The thrombolytic properties in vitro of these ILs and their interactions with two kinds of serum albumins were also studied. This study provides key data and lays foundation for further applications of ILs and risk assessments in related fields.
ISSN:1751-8253
1751-7192