Modeling omics dose-response at the pathway level with DoseRider

The generation of omics data sets has become an important approach in modern pharmacological and toxicological research as it can provide mechanistic and quantitative information on a large scale. Analyses of these data frequently revealed a non-linear dose-response relationship underscoring the imp...

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Bibliographic Details
Published in:	Computational and Structural Biotechnology Journal
Main Authors:	Pablo Monfort-Lanzas, Johanna M. Gostner, Hubert Hackl
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Subjects:	Benchmark dose Dose-response modeling Mixed models Multi-omics System biology Trend change dose
Online Access:	http://www.sciencedirect.com/science/article/pii/S2001037025001266

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