Design principles of a microtubule polymerase

Stu2/XMAP215 microtubule polymerases use multiple tubulin-binding TOG domains and a lattice-binding basic region to processively promote faster elongation. How the domain composition and organization of these proteins dictate polymerase activity, end localization, and processivity is unknown. We sho...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	eLife
المؤلفون الرئيسيون:	Elisabeth A Geyer, Matthew P Miller, Chad A Brautigam, Sue Biggins, Luke M Rice
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	eLife Sciences Publications Ltd 2018-06-01
الموضوعات:	Microtubule dynamics Microtubule polymerase In vitro reconstitution
الوصول للمادة أونلاين:	https://elifesciences.org/articles/34574

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