The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System
The Rho GTPases comprise a subfamily of the Ras superfamily of small GTPases. Their importance in regulation of cell morphology and cell migration is well characterized. According to the prevailing paradigm, Cdc42 regulates the formation of filopodia, Rac1 regulates the formation of lamellipodia, an...
| 出版年: | Cells |
|---|---|
| 第一著者: | Pontus Aspenström |
| フォーマット: | 論文 |
| 言語: | 英語 |
| 出版事項: |
MDPI AG
2019-07-01
|
| 主題: | |
| オンライン・アクセス: | https://www.mdpi.com/2073-4409/8/7/759 |
類似資料
Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling
著者:: Erik Wåhlén, 等
出版事項: (2024-12-01)
著者:: Erik Wåhlén, 等
出版事項: (2024-12-01)
RHOG Activates RAC1 through CDC42 Leading to Tube Formation in Vascular Endothelial Cells
著者:: Oula El Atat, 等
出版事項: (2019-02-01)
著者:: Oula El Atat, 等
出版事項: (2019-02-01)
Equine Alphaherpesviruses Require Activation of the Small GTPases Rac1 and Cdc42 for Intracellular Transport
著者:: Oleksandr Kolyvushko, 等
出版事項: (2020-07-01)
著者:: Oleksandr Kolyvushko, 等
出版事項: (2020-07-01)
Rho GTPases: Big Players in Breast Cancer Initiation, Metastasis and Therapeutic Responses
著者:: Brock Humphries, 等
出版事項: (2020-09-01)
著者:: Brock Humphries, 等
出版事項: (2020-09-01)
Rho GTPases Signaling in Zebrafish Development and Disease
著者:: Marie-José Boueid, 等
出版事項: (2020-12-01)
著者:: Marie-José Boueid, 等
出版事項: (2020-12-01)
Delta-Catenin as a Modulator of Rho GTPases in Neurons
著者:: Maxsam S. Donta, 等
出版事項: (2022-07-01)
著者:: Maxsam S. Donta, 等
出版事項: (2022-07-01)
Rho GTPases and their downstream effectors in megakaryocyte biology
著者:: Irina Pleines, 等
出版事項: (2019-01-01)
著者:: Irina Pleines, 等
出版事項: (2019-01-01)
RHO GTPase family in hepatocellular carcinoma
著者:: Tiantian Wang, 等
出版事項: (2022-11-01)
著者:: Tiantian Wang, 等
出版事項: (2022-11-01)
Uncovering the secret life of Rho GTPases
著者:: Jenna A Perry, 等
出版事項: (2019-12-01)
著者:: Jenna A Perry, 等
出版事項: (2019-12-01)
Cdc42 deletion yielded enamel defects by disrupting mitochondria and producing reactive oxygen species in dental epithelium
著者:: Jinxuan Zheng, 等
出版事項: (2024-09-01)
著者:: Jinxuan Zheng, 等
出版事項: (2024-09-01)
Structural Mechanisms and Drug Discovery Prospects of Rho GTPases
著者:: Cameron C. Smithers, 等
出版事項: (2016-06-01)
著者:: Cameron C. Smithers, 等
出版事項: (2016-06-01)
Coordination between Rac1 and Rab Proteins: Functional Implications in Health and Disease
著者:: Azzurra Margiotta, 等
出版事項: (2019-04-01)
著者:: Azzurra Margiotta, 等
出版事項: (2019-04-01)
Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi
著者:: Alexis Bonfim-Melo, 等
出版事項: (2018-02-01)
著者:: Alexis Bonfim-Melo, 等
出版事項: (2018-02-01)
Rho Family of Ras-Like GTPases in Early-Branching Animals
著者:: Silvestar Beljan, 等
出版事項: (2020-10-01)
著者:: Silvestar Beljan, 等
出版事項: (2020-10-01)
ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization
著者:: Katarzyna Bogucka-Janczi, 等
出版事項: (2023-04-01)
著者:: Katarzyna Bogucka-Janczi, 等
出版事項: (2023-04-01)
Polo-like kinase 1 promotes Cdc42-induced actin polymerization for asymmetric division in oocytes
著者:: Wai Shan Yuen, 等
出版事項: (2023-03-01)
著者:: Wai Shan Yuen, 等
出版事項: (2023-03-01)
Connecting the ends: signaling via receptor tyrosine kinases and cytoskeletal degradation in neurodegeneration
著者:: Priyanka Sengupta, 等
出版事項: (2024-02-01)
著者:: Priyanka Sengupta, 等
出版事項: (2024-02-01)
The RhoGAP activity of CYK-4/MgcRacGAP functions non-canonically by promoting RhoA activation during cytokinesis
著者:: Donglei Zhang, 等
出版事項: (2015-08-01)
著者:: Donglei Zhang, 等
出版事項: (2015-08-01)
NLRP4E regulates actin cap formation through SRC and CDC42 during oocyte meiosis
著者:: Li-Ya Shi, 等
出版事項: (2024-05-01)
著者:: Li-Ya Shi, 等
出版事項: (2024-05-01)
Functionally redundant Rho GTPases Cdc42 and RacA regulate aflatoxin synthesis and pathogenicity in Aspergillus flavus by controlling morphogenesis, oxidative balance and energy metabolism
著者:: Jia Xu, 等
出版事項: (2025-07-01)
著者:: Jia Xu, 等
出版事項: (2025-07-01)
The Small GTPase Cdc42 Is a Major Regulator of Neutrophil Effector Functions
著者:: Heidi Tackenberg, 等
出版事項: (2020-06-01)
著者:: Heidi Tackenberg, 等
出版事項: (2020-06-01)
Coordinated regulation of Cdc42ep1, actin, and septin filaments during neural crest cell migration
著者:: Mary Kho, 等
出版事項: (2023-02-01)
著者:: Mary Kho, 等
出版事項: (2023-02-01)
Efficacy and delivery strategies of the dual Rac/Cdc42 inhibitor MBQ-167 in HER2 overexpressing breast cancer
著者:: Luis E. Velázquez-Vega, 等
出版事項: (2024-06-01)
著者:: Luis E. Velázquez-Vega, 等
出版事項: (2024-06-01)
Modulation of the Pol II CTD Phosphorylation Code by Rac1 and Cdc42 Small GTPases in Cultured Human Cancer Cells and Its Implication for Developing a Synthetic-Lethal Cancer Therapy
著者:: Bo Zhang, 等
出版事項: (2020-03-01)
著者:: Bo Zhang, 等
出版事項: (2020-03-01)
Multiscale Modeling of Bistability in the Yeast Polarity Circuit
著者:: Siarhei Hladyshau, 等
出版事項: (2024-08-01)
著者:: Siarhei Hladyshau, 等
出版事項: (2024-08-01)
Rho GTPases in Skeletal Muscle Development and Homeostasis
著者:: Sonia Rodríguez-Fdez, 等
出版事項: (2021-11-01)
著者:: Sonia Rodríguez-Fdez, 等
出版事項: (2021-11-01)
Cdc42 Effector Protein 3 Interacts With Cdc42 in Regulating Xenopus Somite Segmentation
著者:: Mary Kho, 等
出版事項: (2019-05-01)
著者:: Mary Kho, 等
出版事項: (2019-05-01)
The Wingless planar cell polarity pathway is essential for optimal activity-dependent synaptic plasticity
著者:: Carihann Dominicci-Cotto, 等
出版事項: (2024-04-01)
著者:: Carihann Dominicci-Cotto, 等
出版事項: (2024-04-01)
Overexpression of CDC42SE1 in A431 Cells Reduced Cell Proliferation by Inhibiting the Akt Pathway
著者:: Pazhanichamy Kalailingam, 等
出版事項: (2019-02-01)
著者:: Pazhanichamy Kalailingam, 等
出版事項: (2019-02-01)
The Multiple Functions of Rho GTPases in Fission Yeasts
著者:: Jero Vicente-Soler, 等
出版事項: (2021-06-01)
著者:: Jero Vicente-Soler, 等
出版事項: (2021-06-01)
RhoA and Rac1 in Liver Cancer Cells: Induction of Overexpression Using Mechanical Stimulation
著者:: Sharda Yadav, 等
出版事項: (2020-07-01)
著者:: Sharda Yadav, 等
出版事項: (2020-07-01)
Rho Family GTPases in Fission Yeast Cytokinesis
著者:: Brian Hercyk, 等
出版事項: (2019-01-01)
著者:: Brian Hercyk, 等
出版事項: (2019-01-01)
Rac1 as a Target to Treat Dysfunctions and Cancer of the Bladder
著者:: Vincent Sauzeau, 等
出版事項: (2022-06-01)
著者:: Vincent Sauzeau, 等
出版事項: (2022-06-01)
RAC1B: A Rho GTPase with Versatile Functions in Malignant Transformation and Tumor Progression
著者:: Catharina Melzer, 等
出版事項: (2019-01-01)
著者:: Catharina Melzer, 等
出版事項: (2019-01-01)
Spatiotemporal Coordination of Rac1 and Cdc42 at the Whole Cell Level during Cell Ruffling
著者:: Siarhei Hladyshau, 等
出版事項: (2023-06-01)
著者:: Siarhei Hladyshau, 等
出版事項: (2023-06-01)
RhoA- and Actin-Dependent Functions of Macrophages from the Rodent Cardiac Transplantation Model Perspective -Timing Is the Essence
著者:: Malgorzata Kloc, 等
出版事項: (2021-01-01)
著者:: Malgorzata Kloc, 等
出版事項: (2021-01-01)
Conventional and Non-Conventional Roles of Non-Muscle Myosin II-Actin in Neuronal Development and Degeneration
著者:: Míriam Javier-Torrent, 等
出版事項: (2020-08-01)
著者:: Míriam Javier-Torrent, 等
出版事項: (2020-08-01)
Fission Yeast Polarization: Modeling Cdc42 Oscillations, Symmetry Breaking, and Zones of Activation and Inhibition
著者:: Bita Khalili, 等
出版事項: (2020-07-01)
著者:: Bita Khalili, 等
出版事項: (2020-07-01)
The Rac3 GTPase in Neuronal Development, Neurodevelopmental Disorders, and Cancer
著者:: Ivan de Curtis
出版事項: (2019-09-01)
著者:: Ivan de Curtis
出版事項: (2019-09-01)
pPe Op inhibits HGC-27 cell proliferation, migration and invasion by upregulating miR-30b-5p and down-regulating the Rac1/Cdc42 pathway
著者:: Xu Wenjun, 等
出版事項: (2022-12-01)
著者:: Xu Wenjun, 等
出版事項: (2022-12-01)
類似資料
-
Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling
著者:: Erik Wåhlén, 等
出版事項: (2024-12-01) -
RHOG Activates RAC1 through CDC42 Leading to Tube Formation in Vascular Endothelial Cells
著者:: Oula El Atat, 等
出版事項: (2019-02-01) -
Equine Alphaherpesviruses Require Activation of the Small GTPases Rac1 and Cdc42 for Intracellular Transport
著者:: Oleksandr Kolyvushko, 等
出版事項: (2020-07-01) -
Rho GTPases: Big Players in Breast Cancer Initiation, Metastasis and Therapeutic Responses
著者:: Brock Humphries, 等
出版事項: (2020-09-01) -
Rho GTPases Signaling in Zebrafish Development and Disease
著者:: Marie-José Boueid, 等
出版事項: (2020-12-01)
