The incidence of Arnold–Chiari malformation in neurological practice

• Published in: Неврология, нейропсихиатрия, психосоматика
• Main Authors: E. A. Kantimirova, N. A. Shnaider, M. M. Petrova, I. G. Strotskaya, N. E. Dutova, O. V. Alekseeva, E. A. Shapovalova
• Format: Article
• Language: Russian
• Published: IMA-PRESS LLC 2016-01-01
• Subjects: arnold–chiari malformation; gender; age; incidence; neurological practice
• Online Access: https://nnp.ima-press.net/nnp/article/view/553
• ISSN: 2074-2711; 2310-1342

Arnold-Chiari malformation (ACM) is a group of congenital hindbrain malformations affecting the structural relationships between the cerebellum, brain stem, top cervical spinal cord, and bones of the skull base. In clinical practice, ACM types 0 and 1 are more common and types 2, 3, and 4 belong to rare severe (often fatal) congenital malformations.Objective: to study gender differences in the incidence of ACM types 0 and 1 in outpatient neurological practice.Patients and methods. A total 2039 case records of outpatients who had visited a neurologist of the Krasnoyarsk University clinic in 2008–2014 were analyzed. Neurological and neuroradiological (1.5 Tesla brain magnetic resonance imaging, phase-contrast spinal cerebral fluid flow imaging) diagnostic techniques were used. 3.4% (70/2039) of cases were randomized according to the criteria of inclusion and exception. An entire sample included 70 ACM patients (median age, 25 [17; 34] years) (30 (42.8–7.1%) men and 40 (57.2–7.1%) women).Results. There was an increase in the incidence of ACM type 1 in the women than in the men. Conclusion. It is necessary to develop a new strategy for the prophylactic medical examination of patients with ACM to improve primary and specialized outpatient health care.