| Summary: | Abstract The Zee-Babu model is an economical framework for neutrino mass generation as two-loop quantum corrections. In this work, we present a UV completion of this model by embedding it into an SU(5) unified framework. Interestingly, we find that loop-induced contributions to neutrino masses arising from colored scalars are just as important as those from color-neutral ones. These new states, which are required from gauge coupling unification and neutrino oscillation data to have masses below $$\mathcal{O}$$ (103) TeV, may be accessible to future collider experiments. Additionally, the model can be probed in proton decay searches. Our Markov chain Monte Carlo analysis of model parameters shows a high likelihood of observable p → e + π 0 decay signal in the first decade of Hyper-Kamiokande operation. The model predicts a vector-like down-type quark at the TeV scale, utilized for realistic fermion mass generation and gauge coupling unification. The model is UV-complete in the sense that it is a unified theory which is realistic and asymptotically free that can be extrapolated to the Planck scale.
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