p53/MicroRNA-34 axis in cancer and beyond

Cancer is serious endangers human life. After a long period of research and accumulation, people's understanding of cancer and the corresponding treatment methods are constantly developing. p53 is an important tumor suppressor gene. With the more in-depth understanding of the structure and func...

Full description

Bibliographic Details
Published in:	Heliyon
Main Authors:	Wei Pan, Binshu Chai, Langping Li, Zhijun Lu, Zhongliang Ma
Format:	Article
Language:	English
Published:	Elsevier 2023-04-01
Subjects:	miR-34 p53 Signaling pathway Tumor
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023023629

Similar Items

Hypermethylation of microRNA-34c CpG Island predicts unfavorable prognosis in acute myeloid leukemia
by: Dongqin Yang, et al.
Published: (2025-10-01)

The downregulation of ATG4B mediated by microRNA-34a/34c-5p suppresses rapamycin-induced autophagy
by: Yaran Wu, et al.
Published: (2017-10-01)

Methylation of p53-responsive oncosuppressive microRNA genes in hemoblastosis
by: E. N. Voropaeva, et al.
Published: (2022-05-01)

MicroRNA-34 and gastrointestinal cancers: a player with big functions
by: Wei Gao, et al.
Published: (2024-05-01)

RETRACTED: Oxaliplatin activates P53/miR‐34a/survivin axis in inhibiting the progression of gastric cancer cells
by: Qiang Guo, et al.
Published: (2024-09-01)

The p53/miR-34a/SIRT1 Positive Feedback Loop in Quercetin-Induced Apoptosis
by: Guohua Lou, et al.
Published: (2015-04-01)

MicroRNA-34a Attenuates Metastasis and Chemoresistance of Bladder Cancer Cells by Targeting the TCF1/LEF1 Axis
by: Xiaobing Liu, et al.
Published: (2018-07-01)

The interrelationships between the microRNA miR-34a and the plant flavonoids apigenin and quercetin in the regulation of ovarian cell functions
by: Alexander V. Sirotkin, et al.
Published: (2025-07-01)

MicroRNA-34a functions as an anti-metastatic microRNA and suppresses angiogenesis in bladder cancer by directly targeting CD44
by: Gan Yu, et al.
Published: (2014-12-01)

Role of microRNA miR-34a in liver cancer stem cells
by: Lu-Lu Gong, et al.
Published: (2016-03-01)

MicroRNAs in cancers and neurodegenerative disorders
by: Yoshimasa eSaito, et al.
Published: (2012-09-01)

MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood
by: Paul J Mintz, et al.
Published: (2012-01-01)

MicroRNA-34a and MicroRNA-181a Mediate Visfatin-Induced Apoptosis and Oxidative Stress via NF-κB Pathway in Human Osteoarthritic Chondrocytes
by: Sara Cheleschi, et al.
Published: (2019-08-01)

Double in situ hybridization for microRNAs and mRNAs in brain tissues
by: Atsushi Kasai, et al.
Published: (2016-11-01)

Mechanisms of impaired expression of p53-responsive microRNA genes in diffuse B-large cell lymphoma
by: E. N. Voropaeva, et al.
Published: (2023-10-01)

Inhibition of miR‐34a‐5p can rescue disruption of the p53‐DAPK axis to suppress progression of clear cell renal cell carcinoma
by: Zhi‐Fei Jing, et al.
Published: (2019-10-01)

MicroRNA-34a Attenuates Paclitaxel Resistance in Prostate Cancer Cells via Direct Suppression of JAG1/Notch1 Axis
by: Xiaobing Liu, et al.
Published: (2018-10-01)

MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities
by: Menaka C. Thounaojam, et al.
Published: (2019-08-01)

Indolo‐pyrido‐isoquinolin based alkaloid inhibits growth, invasion and migration of breast cancer cells via activation of p53‐miR34a axis
by: Dimiter B. Avtanski, et al.
Published: (2016-08-01)

Chronic periodontitis and its related microRNA
by: ZHANG Zhen, et al.
Published: (2016-06-01)

MicroRNA-34-5p regulates the expression of ecdysteroid receptor (ECR) in the process of salivary gland degeneration of ticks
by: Shanming Hu, et al.
Published: (2025-05-01)

Role of microRNA-34a in blood–brain barrier permeability and mitochondrial function in ischemic stroke
by: Cole T. Payne, et al.
Published: (2023-10-01)

A functional polymorphism rs4938723 in the promoter of miR-34b/c is associated with an increased risk of lung cancer
by: Aycan ÇELİK, et al.
Published: (2023-12-01)

miR-15/107 microRNA Gene Group: Characteristics and Functional Implications in Cancer
by: Chiara Turco, et al.
Published: (2020-06-01)

3,6-Dihydroxyflavone regulates microRNA-34a through DNA methylation
by: Xiaoli Peng, et al.
Published: (2017-09-01)

Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
by: Jia Li, et al.
Published: (2015-07-01)

From follicle to blastocyst: microRNA-34c from follicular fluid-derived extracellular vesicles modulates blastocyst quality
by: Camilla Benedetti, et al.
Published: (2024-08-01)

MALAT1 Expression Is Deregulated in miR-34a Knockout Cell Lines
by: Andrea Corsi, et al.
Published: (2025-08-01)

Elevated expression of microRNA-155, microRNA-383, and microRNA-9 in Iranian patients with polycystic ovary syndrome
by: Maryam Faraji, et al.
Published: (2025-06-01)

Sperm-borne microRNA-34c regulates maternal mRNA degradation and preimplantation embryonic development in mice
by: Long Cui, et al.
Published: (2023-04-01)

Gymnotic uptake of AntimiRs alter microRNA-34a levels in 2D and 3D epithelial cell culture
by: Julie Weidner, et al.
Published: (2023-09-01)

MicroRNA‐126 in dogs with immune complex‐mediated glomerulonephritis
by: Ariana D. Cherry, et al.
Published: (2024-01-01)

MicroRNA-34a-5p: A pivotal therapeutic target in gallbladder cancer
by: Takashi Oda, et al.
Published: (2024-03-01)

miR-34a and miR-21 as biomarkers in evaluating the response of chemo-radiotherapy in Egyptian breast cancer patients
by: Nadia Z. Shaban, et al.
Published: (2022-09-01)

The role of miR-16 and miR-34a family in the regulation of cancers: A review
by: Zahra Sadeghi, et al.
Published: (2025-02-01)

MiRNA 34-a regulate SIRT-1 and Foxo-1 expression in endometriosis
by: Noha A. Rezk, et al.
Published: (2021-03-01)

MicroRNA-9 controls dendritic development by targeting REST
by: Sebastian A Giusti, et al.
Published: (2014-11-01)

ROS-induced imbalance of the miR-34a-5p/SIRT1/p53 axis triggers chronic chondrocyte injury and inflammation
by: Meng Zhou, et al.
Published: (2024-06-01)

Evaluation of Organoid‐Derived Exosomal microRNA as Liquid Biopsy for Colorectal Cancer: A Multicenter Cross‐Sectional Study
by: Atsuhiro Sasaki, et al.
Published: (2025-06-01)

Bio-engineered microRNA-7 effectively interferes with the Akt3/p53 axis to suppress human non-small cell lung cancer
by: Qian Huang, et al.
Published: (2025-07-01)