A case of late presentation of precocious puberty due to pituitary astrocytoma
The importance of assessing precocious puberty, especially in boys, is not only due to the great complications it has for the affected patients, but also to the fatal underlying diseases. Therefore, children with central precocious puberty should first undergo neuroimaging. In this case study, we...
| Published in: | Aktualności Neurologiczne |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
Medical Communications Sp. z o.o.
2015-08-01
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| Subjects: | |
| Online Access: | http://neurologia.com.pl/index.php/issues/2015-vol-15-no-2/a-case-of-late-presentation-of-precocious-puberty-due-to-pituitary-astrocytoma?aid=821 |
| Summary: | The importance of assessing precocious puberty, especially in boys, is not only due to the great complications it has for
the affected patients, but also to the fatal underlying diseases. Therefore, children with central precocious puberty should
first undergo neuroimaging. In this case study, we present a 9.5-year-old boy who was referred to Rasoul-e-Akram Medical
Center with increased intracranial pressure, nausea/vomiting, and severe headache having begun three months earlier.
The development of secondary sexual changes had started two years earlier, and had been neglected. His testes, penis, and
pubic hair were at the fourth Tanner stage. He had elevated luteinizing and follicle stimulating hormones. Microscopic
evaluation confirmed low-grade pilocytic astrocytoma WHO grade 1. Emergency brain surgery was conducted in which
the brain was decompressed, and chemotherapy was started postoperatively. Two years after the surgery, he remains under
chemotherapy, with obvious sexual maturation and a height of 154 cm. Training families and medical staff efficiently can
help prevent the late diagnosis and treatment of precocious puberty and, as a result, help patients in their social life. |
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| ISSN: | 1641-9227 2451-0696 |