Selective Suppression of Integrin‐Ligand Binding by Single Molecular Tension Probes Mediates Directional Cell Migration

Abstract Cell migration interacting with continuously changing microenvironment, is one of the most essential cellular functions, participating in embryonic development, wound repair, immune response, and cancer metastasis. The migration process is finely tuned by integrin‐mediated binding to ligand...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Advanced Science
المؤلفون الرئيسيون:	Seong‐Beom Han, Geonhui Lee, Daesan Kim, Jeong‐Ki Kim, In‐San Kim, Hae‐Won Kim, Dong‐Hwee Kim
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Wiley 2024-04-01
الموضوعات:	cell adhesion FAK phosphorylation integrin αvβ3 molecular tension probes persistent migration
الوصول للمادة أونلاين:	https://doi.org/10.1002/advs.202306497

مواد مشابهة

Recycling machinery of integrin coupled with focal adhesion turnover via RAB11-UNC13D-FAK axis for migration of pancreatic cancer cells
حسب: Van-Thanh Duong, وآخرون
منشور في: (2024-08-01)

The activation of CD99 inhibits cell-extracellular matrix adhesion by suppressing β1 integrin affinity
حسب: Kyoung-Jin Lee, وآخرون
منشور في: (2012-03-01)

RITA modulates cell migration and invasion by affecting focal adhesion dynamics
حسب: Samira Catharina Hoock, وآخرون
منشور في: (2019-10-01)

Focal Adhesion’s Role in Cardiomyocytes Function: From Cardiomyogenesis to Mechanotransduction
حسب: Simona Casarella, وآخرون
منشور في: (2024-04-01)

DIRAS3 Inhibits Ovarian Cancer Cell Growth by Blocking the Fibronectin-Mediated Integrin β1/FAK/AKT Signaling Pathway
حسب: Jing Guo, وآخرون
منشور في: (2025-08-01)

<i>Smilax glabra</i> Roxb. Inhibits Collagen Induced Adhesion and Migration of PC3 and LNCaP Prostate Cancer Cells through the Inhibition of Beta 1 Integrin Expression
حسب: Oh Yun Kwon, وآخرون
منشور في: (2020-06-01)

Integrin-Mediated Adhesion Promotes Centrosome Separation in Early Mitosis
حسب: Siamak A. Kamranvar, وآخرون
منشور في: (2022-04-01)

Integrins linked kinase and focal adhesion kinase as the key signaling mediators of vascular mimicry in metastatic breast tumor cells
حسب: Mohammad Kamalabadi-Farahani, وآخرون
منشور في: (2024-10-01)

Novel role of Dipterocarpus tuberculatus as a stimulator of focal cell adhesion through the regulation of MLC2/FAK/Akt signaling pathway
حسب: Su Jin Lee, وآخرون
منشور في: (2022-12-01)

Regulation of Dynamic Cell Adhesion by Integrin-Integrin Crosstalk
حسب: Carl G. Gahmberg, وآخرون
منشور في: (2022-05-01)

Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility
حسب: Wang Wenqi, وآخرون
منشور في: (2011-11-01)

Fibroblast growth factor receptor 4 promotes glioblastoma progression: a central role of integrin-mediated cell invasiveness
حسب: Lisa Gabler, وآخرون
منشور في: (2022-04-01)

Dietary Polyphenols Effects on Focal Adhesion Plaques and Metalloproteinases in Cancer Invasiveness
حسب: Raffaele Carrano, وآخرون
منشور في: (2024-02-01)

Nanoporous titanium implant surface promotes osteogenesis by suppressing osteoclastogenesis via integrin β1/FAKpY397/MAPK pathway
حسب: Yide He, وآخرون
منشور في: (2022-02-01)

TMEM182 interacts with integrin beta 1 and regulates myoblast differentiation and muscle regeneration
حسب: Wen Luo, وآخرون
منشور في: (2021-12-01)

Recent Advances in Cell Adhesive Force Microscopy
حسب: Ying Tu, وآخرون
منشور في: (2020-12-01)

Signal Transduction Mechanisms of Focal Adhesions: Src and FAK-Mediated Cell Response
حسب: Kazuo Katoh
منشور في: (2024-11-01)

PI3K-AKT activation resculpts integrin signaling to drive filamentous tau-induced proinflammatory astrogliosis
حسب: Peng Wang, وآخرون
منشور في: (2023-09-01)

PRR11 induces filopodia formation and promotes cell motility via recruiting ARP2/3 complex in non-small cell lung cancer cells
حسب: Zhili Wei, وآخرون
منشور في: (2022-01-01)

Cilengitide inhibits osteoclast adhesion through blocking the αvβ3-mediated FAK/Src signaling pathway
حسب: Dan-yang Guo, وآخرون
منشور في: (2023-07-01)

Inhibition of Integrin αvβ3-FAK-MAPK signaling constrains the invasion of T-ALL cells
حسب: Lan Huang, وآخرون
منشور في: (2023-12-01)

Nascent Adhesion Clustering: Integrin-Integrin and Integrin-Substrate Interactions
حسب: Kuanpo Lin, وآخرون
منشور في: (2022-01-01)

Clinical significance of integrin αV and β superfamily members and focal adhesion kinase activity in oral squamous cell carcinoma: a retrospective observational study
حسب: Shigeru Sakurai, وآخرون
منشور في: (2024-01-01)

Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension
حسب: Joanna P Rys, وآخرون
منشور في: (2015-12-01)

Integrin force loading rate in mechanobiology: From model to molecular measurement
حسب: Hongyuan Zhang, وآخرون
منشور في: (2025-01-01)

Interplay of integrins and selectins in metastasis
حسب: Diana Maltseva, وآخرون
منشور في: (2025-06-01)

β<sub>2</sub>-Integrin Adhesive Bond Tension under Shear Stress Modulates Cytosolic Calcium Flux and Neutrophil Inflammatory Response
حسب: Vasilios Aris Morikis, وآخرون
منشور في: (2022-09-01)

Integrin β5 interacts with G3BP1 through activating FAK/Src signaling pathway to promote gastric carcinogenesis
حسب: Dongliang Liu, وآخرون
منشور في: (2025-08-01)

The Actin Network Interfacing Diverse Integrin-Mediated Adhesions
حسب: Benjamin Geiger, وآخرون
منشور في: (2023-02-01)

Regulation of Renin Expression by Β1-Integrin in As4.1 Juxtaglomerular Line Cells
حسب: Nobumichi Saito, وآخرون
منشور في: (2023-02-01)

Role of Integrin Alpha4 in Drug Resistance of Leukemia
حسب: Yong-Mi eKim, وآخرون
منشور في: (2014-05-01)

Nanoscopy reveals integrin clustering reliant on kindlin-3 but not talin-1
حسب: Yuanyuan Wu, وآخرون
منشور في: (2025-01-01)

Myosin-X and talin modulate integrin activity at filopodia tips
حسب: Mitro Miihkinen, وآخرون
منشور في: (2021-09-01)

Galectin 3‐binding protein (LGALS3BP) depletion attenuates hepatic fibrosis by reducing transforming growth factor‐β1 (TGF‐β1) availability and inhibits hepatocarcinogenesis
حسب: Dae‐Hwan Kim, وآخرون
منشور في: (2024-10-01)

Cell Cycle Regulation by Integrin-Mediated Adhesion
حسب: Siamak A. Kamranvar, وآخرون
منشور في: (2022-08-01)

Dimensions and dynamics in integrin function
حسب: K.M. Yamada, وآخرون
منشور في: (2003-08-01)

Beta2-Integrins and Interacting Proteins in Leukocyte Trafficking, Immune Suppression, and Immunodeficiency Disease
حسب: Susanna C. Fagerholm, وآخرون
منشور في: (2019-02-01)

Heparan sulfate proteoglycans remodel SARS-CoV-2 spike conformation to allow integrin interaction and infection of endothelial cells
حسب: Antonella Bugatti, وآخرون
منشور في: (2025-04-01)

Development and biological characterization of the cyclic peptide cRGDTFI with potent binding affinity for integrins αvβ3 and αvβ5
حسب: Yuji Yamada, وآخرون
منشور في: (2025-09-01)

Are integrins and ligands correlated at pig placental interface during pregnancy?
حسب: Velez Carolina, وآخرون
منشور في: (2023-03-01)