GBV-C/HGV and HIV-1 coinfection

An interesting interaction pattern has been found between HIV-1 and GBV-C/HGV, resulting in protection against progression to AIDS. The mechanisms involved in this interaction remain to be clarified. We examined the current knowledge concerning this coinfection and developed hypotheses to explain it...

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Bibliographic Details
Published in:Brazilian Journal of Infectious Diseases
Main Authors: Maria Teresa Maidana, Ester Cerdeira Sabino, Esper Georges Kallas
Format: Article
Language:English
Published: Elsevier
Subjects:
HIV
HGV
GBV-C
pathogenesis
review
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000200001&lng=en&tlng=en
Description
Summary:An interesting interaction pattern has been found between HIV-1 and GBV-C/HGV, resulting in protection against progression to AIDS. The mechanisms involved in this interaction remain to be clarified. We examined the current knowledge concerning this coinfection and developed hypotheses to explain its effects. A better understanding of this interaction could result in new concepts, which may lead to new strategies to control HIV-1 replication and progression to AIDS.
ISSN:1678-4391

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