Treatment with Exogenous Trypsin Expands In Vitro Cellular Tropism of the Avian Coronavirus Infectious Bronchitis Virus

The <i>Gammacoronavirus</i> infectious bronchitis virus (IBV) causes a highly contagious and economically important respiratory disease in poultry. In the laboratory, most IBV strains are restricted to replication in ex vivo organ cultures or in ovo and do not replicate in cell culture,...

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Bibliographic Details
Published in:	Viruses
Main Authors:	Phoebe Stevenson-Leggett, Sarah Keep, Erica Bickerton
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Subjects:	coronavirus animal coronavirus cleavage tropism glycoprotein spike protein
Online Access:	https://www.mdpi.com/1999-4915/12/10/1102

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