Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice

Abstract Reactive oxygen species (ROS) can induce oxidative injury and are generally regarded as toxic byproducts, although they are increasingly recognized for their signaling functions. Increased ROS often accompanies liver regeneration (LR) after liver injuries, however, their role in LR and the...

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Bibliographic Details
Published in:Cell Death and Disease
Main Authors: Hua Bai, Cong-Wen Fang, Ying Shi, Song Zhai, An Jiang, Ying-Na Li, Lin Wang, Qi-Ling Liu, Geng-Yao Zhou, Jia-Hao Cao, Jia Li, Xue-Kang Yang, Xu-Jun Qin
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Online Access:https://doi.org/10.1038/s41419-023-05744-w

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