Dermis resident macrophages orchestrate localized ILC2 eosinophil circuitries to promote non-healing cutaneous leishmaniasis
Abstract Tissue-resident macrophages are critical for tissue homeostasis and repair. We previously showed that dermis-resident macrophages produce CCL24 which mediates their interaction with IL-4+ eosinophils, required to maintain their M2-like properties in the TH1 environment of the Leishmania maj...
| Published in: | Nature Communications |
|---|---|
| Main Authors: | Sang Hun Lee, Byunghyun Kang, Olena Kamenyeva, Tiago Rodrigues Ferreira, Kyoungin Cho, Jaspal S. Khillan, Juraj Kabat, Brian L. Kelsall, David L. Sacks |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-11-01
|
| Online Access: | https://doi.org/10.1038/s41467-023-43588-2 |
Similar Items
Kupffer cell and recruited macrophage heterogeneity orchestrate granuloma maturation and hepatic immunity in visceral leishmaniasis
by: Gabriela Pessenda, et al.
Published: (2025-04-01)
by: Gabriela Pessenda, et al.
Published: (2025-04-01)
Resilience of dermis resident macrophages to inflammatory challenges
by: Sang Hun Lee, et al.
Published: (2024-10-01)
by: Sang Hun Lee, et al.
Published: (2024-10-01)
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation
by: Claire Pearson, et al.
Published: (2016-01-01)
by: Claire Pearson, et al.
Published: (2016-01-01)
A role for IL-33–activated ILC2s in eosinophilic vasculitis
by: Maya E. Kotas, et al.
Published: (2021-06-01)
by: Maya E. Kotas, et al.
Published: (2021-06-01)
Preparation of Animals with a High Degree of Chimerism by One-Step Coculture of Embryonic Stem Cells and Preimplantation Embryos
by: Jaspal S. Khillan, et al.
Published: (1997-03-01)
by: Jaspal S. Khillan, et al.
Published: (1997-03-01)
Regeneration of Dermis: Scarring and Cells Involved
by: Alexandra L. Rippa, et al.
Published: (2019-06-01)
by: Alexandra L. Rippa, et al.
Published: (2019-06-01)
Basophils Orchestrating Eosinophils’ Chemotaxis and Function in Allergic Inflammation
by: Joseena Iype, et al.
Published: (2021-04-01)
by: Joseena Iype, et al.
Published: (2021-04-01)
Non-allergic eosinophilic inflammation and airway hyperresponsiveness induced by diesel engine exhaust through activating ILCs
by: Huasi Zhao, et al.
Published: (2024-06-01)
by: Huasi Zhao, et al.
Published: (2024-06-01)
Extra Cellular Matrix Deposition and Assembly in Dermis Spheroids
by: Rescigno F, et al.
Published: (2021-07-01)
by: Rescigno F, et al.
Published: (2021-07-01)
Elastolisis de la dermis media
by: Gerzaín Rodríguez
Published: (2019-02-01)
by: Gerzaín Rodríguez
Published: (2019-02-01)
Granuloma Caused by Carbon Deposition in the Dermis
by: Rintaro Shibuya, et al.
Published: (2014-01-01)
by: Rintaro Shibuya, et al.
Published: (2014-01-01)
Targeting the dermis for melasma maintenance treatment
by: Hee Jeong Han, et al.
Published: (2024-01-01)
by: Hee Jeong Han, et al.
Published: (2024-01-01)
Rapamycin Dampens Inflammatory Properties of Bone Marrow ILC2s in IL-33-Induced Eosinophilic Airway Inflammation
by: Emma Boberg, et al.
Published: (2022-06-01)
by: Emma Boberg, et al.
Published: (2022-06-01)
Comparison of Tissue-Engineered Dermis with Micronized Adipose Tissue and Artificial Dermis for Facial Reconstruction Following Skin Cancer Resection
by: Kyu-Il Lee, et al.
Published: (2025-02-01)
by: Kyu-Il Lee, et al.
Published: (2025-02-01)
Illuminating T cell-dendritic cell interactions in vivo by FlAsHing antigens
by: Munir Akkaya, et al.
Published: (2024-01-01)
by: Munir Akkaya, et al.
Published: (2024-01-01)
Eosinophils of patients with localized and diffuse cutaneous leishmaniasis: Differential response to Leishmania mexicana, with insights into mechanisms of damage inflicted upon the parasites by eosinophils.
by: Norma Salaiza-Suazo, et al.
Published: (2024-01-01)
by: Norma Salaiza-Suazo, et al.
Published: (2024-01-01)
Eosinophils of patients with localized and diffuse cutaneous leishmaniasis: Differential response to Leishmania mexicana, with insights into mechanisms of damage inflicted upon the parasites by eosinophils
by: Norma Salaiza-Suazo, et al.
Published: (2024-01-01)
by: Norma Salaiza-Suazo, et al.
Published: (2024-01-01)
B cell dependent T lymphocyte responses in leishmaniasis
by: David L. Sacks
Published: (1988-11-01)
by: David L. Sacks
Published: (1988-11-01)
B cell dependent T lymphocyte responses in leishmaniasis
by: David L. Sacks
Published: (1987-11-01)
by: David L. Sacks
Published: (1987-11-01)
The efficacy of artificial dermis for wound repair after resection of cutaneous malignant tumors
by: Jianjian LI, et al.
Published: (2023-06-01)
by: Jianjian LI, et al.
Published: (2023-06-01)
PI3Kδ inhibition prevents IL33, ILC2s and inflammatory eosinophils in persistent airway inflammation
by: Sorif Uddin, et al.
Published: (2021-12-01)
by: Sorif Uddin, et al.
Published: (2021-12-01)
Mid-dermis Grafting—A Clinical Study
by: N. K. Mehdiratta, et al.
Published: (1975-07-01)
by: N. K. Mehdiratta, et al.
Published: (1975-07-01)
Decellularized Human Dermis for Orthoplastic Extremity Reconstruction
by: Christopher Bibbo, et al.
Published: (2024-04-01)
by: Christopher Bibbo, et al.
Published: (2024-04-01)
Is Stress Relaxation in Sea Cucumber Dermis Chemoelastic?
by: Ettore Barbieri, et al.
Published: (2023-11-01)
by: Ettore Barbieri, et al.
Published: (2023-11-01)
Acellular Piscine Dermis for Pediatric Hand Burn Reconstruction
by: Shawhin R.K. Shahriari, MD, et al.
Published: (2024-07-01)
by: Shawhin R.K. Shahriari, MD, et al.
Published: (2024-07-01)
The circuitry of sex
by: Joel Levine
Published: (2016-11-01)
by: Joel Levine
Published: (2016-11-01)
ILC Vanguard Initiative
by: Takahashi Tohru
Published: (2024-01-01)
by: Takahashi Tohru
Published: (2024-01-01)
Regulatory ILC2—Role of IL-10 Producing ILC2 in Asthma
by: Nahal Emami Fard, et al.
Published: (2023-10-01)
by: Nahal Emami Fard, et al.
Published: (2023-10-01)
Unrestrained Gαi2 Signaling Disrupts Neutrophil Trafficking, Aging, and Clearance
by: Serena Li-Sue Yan, et al.
Published: (2021-05-01)
by: Serena Li-Sue Yan, et al.
Published: (2021-05-01)
Investigation of Dermis-derived hydrogels for wound healing applications
by: Holger Engel, et al.
Published: (2015-02-01)
by: Holger Engel, et al.
Published: (2015-02-01)
The microbiota of the surface, dermis and subcutaneous tissue of dog skin
by: Rocío García-Fonticoba, et al.
Published: (2020-09-01)
by: Rocío García-Fonticoba, et al.
Published: (2020-09-01)
Dampened Regulatory Circuitry of TEAD1/ITGA1/ITGA2 Promotes TGFβ1 Signaling to Orchestrate Prostate Cancer Progression
by: Sara P. Cruz, et al.
Published: (2024-03-01)
by: Sara P. Cruz, et al.
Published: (2024-03-01)
ILC Upgrade with Energy Recovery
by: Yokoya Kaoru
Published: (2024-01-01)
by: Yokoya Kaoru
Published: (2024-01-01)
Ulus İlçe Halk Kütüphanesi
by: İsmail Akman
Published: (2008-06-01)
by: İsmail Akman
Published: (2008-06-01)
Transcriptional control of ILC identity
by: Anna A. Korchagina, et al.
Published: (2023-03-01)
by: Anna A. Korchagina, et al.
Published: (2023-03-01)
The Metabolic Basis of ILC Plasticity
by: Abigaelle Pelletier, et al.
Published: (2022-04-01)
by: Abigaelle Pelletier, et al.
Published: (2022-04-01)
Editorial: Heterogeneity of ILC2s
by: Hiroki Kabata, et al.
Published: (2023-06-01)
by: Hiroki Kabata, et al.
Published: (2023-06-01)
ILC2s in skin disorders
by: Yasutomo Imai
Published: (2023-04-01)
by: Yasutomo Imai
Published: (2023-04-01)
Primary Clear Cell Sarcoma of the Dermis Mimicking Malignant Melanoma
by: Ifeyinwa E. Obiorah, et al.
Published: (2018-03-01)
by: Ifeyinwa E. Obiorah, et al.
Published: (2018-03-01)
The Dermis as a Delivery Site of Trypanosoma brucei for Tsetse Flies.
by: Guy Caljon, et al.
Published: (2016-07-01)
by: Guy Caljon, et al.
Published: (2016-07-01)
Similar Items
-
Kupffer cell and recruited macrophage heterogeneity orchestrate granuloma maturation and hepatic immunity in visceral leishmaniasis
by: Gabriela Pessenda, et al.
Published: (2025-04-01) -
Resilience of dermis resident macrophages to inflammatory challenges
by: Sang Hun Lee, et al.
Published: (2024-10-01) -
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation
by: Claire Pearson, et al.
Published: (2016-01-01) -
A role for IL-33–activated ILC2s in eosinophilic vasculitis
by: Maya E. Kotas, et al.
Published: (2021-06-01) -
Preparation of Animals with a High Degree of Chimerism by One-Step Coculture of Embryonic Stem Cells and Preimplantation Embryos
by: Jaspal S. Khillan, et al.
Published: (1997-03-01)
