Next generation sequencing of the clonal IGH rearrangement detects ongoing mutations and interfollicular trafficking in in situ follicular neoplasia.

Follicular lymphoma (FL) is characterized genetically by a significant intraclonal diversity of rearranged immunoglobulin heavy chain (IGH) genes and a substantial cell migration activity (follicular trafficking). Recently, in situ follicular neoplasia (ISFN), characterized by accumulations of immun...

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Bibliographic Details
Published in:	PLoS ONE
Main Authors:	Perikles Kosmidis, Irina Bonzheim, Claudia Dufke, Sema Colak, Thomas Hentrich, Christopher Schroeder, Peter Bauer, Patrick Adam, Falko Fend
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2017-01-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0178503&type=printable

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