Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population
ICGi021-A and ICGi022-A iPSC lines were obtained by reprogramming PBMCs of two healthy women of the Siberian population using episomal non-integrating vectors expressing Yamanaka factors. iPSC lines expressed pluripotency markers, had a normal karyotype and demonstrated the ability to differentiate...
| Published in: | Stem Cell Research |
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| Main Authors: | , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-10-01
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506120302531 |
| _version_ | 1852807505417076736 |
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| author | A.A. Malakhova E.V. Grigor'eva S.V. Pavlova T.B. Malankhanova K.R. Valetdinova Y.V. Vyatkin E.A. Khabarova J.A. Rzaev S.M. Zakian S.P. Medvedev |
| author_facet | A.A. Malakhova E.V. Grigor'eva S.V. Pavlova T.B. Malankhanova K.R. Valetdinova Y.V. Vyatkin E.A. Khabarova J.A. Rzaev S.M. Zakian S.P. Medvedev |
| author_sort | A.A. Malakhova |
| collection | DOAJ |
| container_title | Stem Cell Research |
| description | ICGi021-A and ICGi022-A iPSC lines were obtained by reprogramming PBMCs of two healthy women of the Siberian population using episomal non-integrating vectors expressing Yamanaka factors. iPSC lines expressed pluripotency markers, had a normal karyotype and demonstrated the ability to differentiate into derivatives of the three germ layers. Clinical exome sequencing data of the original biosamples of the donors are available in the NCBI SRA database. The generated cell lines are useful as “healthy” control in biomedical studies. |
| format | Article |
| id | doaj-art-9d8dd950a4cd4f2fa1aadd4fa1c189fa |
| institution | Directory of Open Access Journals |
| issn | 1873-5061 |
| language | English |
| publishDate | 2020-10-01 |
| publisher | Elsevier |
| record_format | Article |
| spelling | doaj-art-9d8dd950a4cd4f2fa1aadd4fa1c189fa2025-08-19T20:37:29ZengElsevierStem Cell Research1873-50612020-10-014810195210.1016/j.scr.2020.101952Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian populationA.A. Malakhova0E.V. Grigor'eva1S.V. Pavlova2T.B. Malankhanova3K.R. Valetdinova4Y.V. Vyatkin5E.A. Khabarova6J.A. Rzaev7S.M. Zakian8S.P. Medvedev9Federal Research Center Institute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; E.N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia; Institute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, Russia; Corresponding author at: Federal Research Center Institute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.Federal Research Center Institute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; E.N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia; Institute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, RussiaFederal Research Center Institute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; E.N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia; Institute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, RussiaFederal Research Center Institute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; E.N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia; Institute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, RussiaFederal Research Center Institute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; E.N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia; Institute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, RussiaNovosibirsk State University, Novosibirsk, Russia; AcademGene LLC, Novosibirsk, RussiaFSBI Federal Neurosurgical Center, Novosibirsk, RussiaFSBI Federal Neurosurgical Center, Novosibirsk, RussiaFederal Research Center Institute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; E.N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia; Institute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, RussiaFederal Research Center Institute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; E.N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia; Institute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, RussiaICGi021-A and ICGi022-A iPSC lines were obtained by reprogramming PBMCs of two healthy women of the Siberian population using episomal non-integrating vectors expressing Yamanaka factors. iPSC lines expressed pluripotency markers, had a normal karyotype and demonstrated the ability to differentiate into derivatives of the three germ layers. Clinical exome sequencing data of the original biosamples of the donors are available in the NCBI SRA database. The generated cell lines are useful as “healthy” control in biomedical studies.http://www.sciencedirect.com/science/article/pii/S1873506120302531 |
| spellingShingle | A.A. Malakhova E.V. Grigor'eva S.V. Pavlova T.B. Malankhanova K.R. Valetdinova Y.V. Vyatkin E.A. Khabarova J.A. Rzaev S.M. Zakian S.P. Medvedev Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population |
| title | Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population |
| title_full | Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population |
| title_fullStr | Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population |
| title_full_unstemmed | Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population |
| title_short | Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population |
| title_sort | generation of induced pluripotent stem cell lines icgi021 a and icgi022 a from peripheral blood mononuclear cells of two healthy individuals from siberian population |
| url | http://www.sciencedirect.com/science/article/pii/S1873506120302531 |
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