Dihydromyricetin suppresses endothelial NLRP3 inflammasome activation and attenuates atherogenesis by promoting mitophagy

Abstract Background NOD-like receptor protein 3 (NLRP3) inflammasome activation is indispensable for atherogenesis. Mitophagy has emerged as a potential strategy to counteract NLRP3 inflammasome activation triggered by impaired mitochondria. Our previous research has indicated that dihydromyricetin,...

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Bibliographic Details
Published in:	Lipids in Health and Disease
Main Authors:	Qin Hu, Chengying Li, Ting Zhang, Long Yi, Yifan Shan, Xiangyu Ma, Tongjian Cai, Li Ran, Hui Shen, Yafei Li
Format:	Article
Language:	English
Published:	BMC 2024-09-01
Subjects:	Atherosclerosis Dihydromyricetin Mitophagy NLRP3 inflammasome Vascular endothelium
Online Access:	https://doi.org/10.1186/s12944-024-02263-1

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