FTY720 controls disease severity and attenuates sciatic nerve damage in chronic experimental autoimmune neuritis

Abstract Background Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune-mediated inflammatory disease of the peripheral nervous system characterized by a response directed against certain myelin proteins and for which therapies are limited. Previous studies have suggest...

Full description

Bibliographic Details
Published in:	Journal of Neuroinflammation
Main Authors:	Laurent Kremer, Omar Taleb, Nelly Boehm, Ayikoe Guy Mensah-Nyagan, Elisabeth Trifilieff, Jérôme de Seze, Susana Brun
Format:	Article
Language:	English
Published:	BMC 2019-03-01
Subjects:	Chronic inflammatory demyelinating polyradiculoneuropathy c-EAN FTY720 Inflammatory neuropathies
Online Access:	http://link.springer.com/article/10.1186/s12974-019-1441-4

Similar Items

Pharmacokinetic/pharmacodynamic relationships of FTY720 in kidney transplant recipients
by: S.I. Park, et al.
Published: (2005-05-01)

Bioinformatics-Based Analysis of the Screening and Evaluation of Potential Targets of FTY720 for the Treatment of Non-Small Cell Lung Cancer
by: Mengyuan Han, et al.
Published: (2025-09-01)

Effect of FTY720 on transfusion-related acute lung injury: a preliminary investigation
by: Yaling ZHOU, et al.
Published: (2023-05-01)

The functional antagonist of sphingosine-1-phosphate, FTY720, impairs gut barrier function
by: Sohini Sikdar, et al.
Published: (2024-08-01)

A genome-wide screen for FTY720-sensitive mutants reveals genes required for ROS homeostasis
by: Kanako Hagihara, et al.
Published: (2017-11-01)

FTY720 in immuno-regenerative and wound healing technologies for muscle, epithelial and bone regeneration
by: Monica Behara, et al.
Published: (2023-05-01)

Anti-tumor drug FTY720 regulates p53-dependent transcription
by: YAO Han, XU Wen-bin, WANG Dong-lai
Published: (2021-03-01)

Behavioral Analyses in Dark Agouti Rats Following Repeated Systemic Treatment With Fingolimod (FTY720)
by: Marie Jakobs, et al.
Published: (2024-11-01)

The Effects of the S1P Receptor Agonist Fingolimod (FTY720) on Central and Peripheral Myelin in Twitcher Mice
by: Sibylle Béchet, et al.
Published: (2024-03-01)

FTY720 Reduces the Biomass of Biofilms in <i>Pseudomonas aeruginosa</i> in a Dose-Dependent Manner
by: Abdurahman A. Niazy, et al.
Published: (2024-07-01)

Effects of FTY720 on brain neurogenic niches in vitro and after kainic acid-induced injury
by: Raffaela Cipriani, et al.
Published: (2017-07-01)

Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis
by: Sahar A. Saddoughi, et al.
Published: (2012-11-01)

Presynaptic Release-Regulating Sphingosine 1-Phosphate 1/3 Receptors in Cortical Glutamatergic Terminals: Adaptations in EAE Mice and Impact of Therapeutic FTY720
by: Alessandra Roggeri, et al.
Published: (2023-09-01)

Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging
by: Jie Zhang, et al.
Published: (2020-01-01)

The Immunosuppressant FTY720 (Fingolimod) enhances Glycosaminoglycan depletion in articular cartilage
by: Stradner Martin H, et al.
Published: (2011-12-01)

Sex-dependent efficacy of sphingosine-1-phosphate receptor agonist FTY720 in mitigating Huntington’s disease
by: Jingyun Wu, et al.
Published: (2025-01-01)

Injectable Hydrogel Loaded with CDs and FTY720 Combined with Neural Stem Cells for the Treatment of Spinal Cord Injury
by: Qi Z, et al.
Published: (2024-05-01)

Chronic inflammatory demyelinating polyradiculoneuropathy associated with Sjögren`s syndrome in a child
by: Nurşah Yeniay Süt, et al.
Published: (2023-02-01)

FTY720 induces apoptosis in B16F10-NEX2 murine melanoma cells, limits metastatic development in vivo, and modulates the immune system
by: Felipe V. Pereira, et al.
Published: (2013-07-01)

Fingolimod ameliorates chronic experimental autoimmune neuritis by modulating inflammatory cytokines and Akt/mTOR/NF‐κB signaling
by: Yuan Feng, et al.
Published: (2023-04-01)

Platelet Membrane Nanocarriers Cascade Targeting Delivery System to Improve Myocardial Remodeling Post Myocardial Ischemia–Reperfusion Injury
by: Xuan Xu, et al.
Published: (2024-04-01)

Clinical and Electrophysiologic Findings of Fatigue in Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A Narrative Review
by: Aysegül Gündüz, et al.
Published: (2024-09-01)

Animal models of immune-mediated demyelinating polyneuropathies
by: Eroboghene E. Ubogu
Published: (2024-12-01)

Chronic Inflammatory Demyelinating Polyradiculoneuropaty: Post-Pandemic Review
by: Hilal Taştekin Toz
Published: (2023-09-01)

Demyelinating Polyradiculoneuropathy in Chronic Lymphocytic Leukemia: A Case Report on BTKis versus Venetoclax-Rituximab
by: Alessandro Cellini, et al.
Published: (2023-12-01)

FTY720-derivatives do not induce FTY720-like lymphopenia
by: Ismael Segura-Ulate, et al.
Published: (2017-03-01)

Brazilian Academy of Neurology recommendations for diagnosis, management, and treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)
by: Osvaldo J. M. Nascimento, et al.
Published: (2025-07-01)

Processing speed impairment in chronic inflammatory demyelinating polyneuropathy patients: a cross-sectional study
by: Iara Senem, et al.
Published: (2022-10-01)

Chronic inflammatory demyelinating polyradiculoneuropathy overdiagnosis in Russia
by: Daria A. Grishina, et al.
Published: (2023-09-01)

Neurophysiological differential diagnostic markers in hereditary neuropathy with liability to pressure palsies and chronic inflammatory demyelinating polyradiculoneuropathy
by: D. A. Grishina, et al.
Published: (2023-03-01)

Case report: Chronic inflammatory demyelinating polyradiculoneuropathy with severe central nervous system demyelination: a clinicopathological study
by: Goichi Beck, et al.
Published: (2024-12-01)

Intravenous Immunoglobulin Initiation in Patients with Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A US Claims-based Cohort Study
by: J. Bradley Layton, et al.
Published: (2023-05-01)

Successful treatment of relapsed and refractory CIDP with ofatumumab: a first case report
by: Jian Wang, et al.
Published: (2024-07-01)

Chronic Inflammatory Polyradiculoneuropathy
by: J Gordon Millichap
Published: (1997-12-01)

Monoclonal Gammopathy Presenting Section as Peripheral Neuropathy
by: Vishaka Agarwal, et al.
Published: (2021-04-01)

Case of Chronic Inflamatory Demyelinating Polyneuropathy: A Reminder
by: Suzan Şaylısoy, et al.
Published: (2011-03-01)

Diagnosis of hereditary transthyretin amyloidosis in patients with suspected chronic inflammatory demyelinating polyneuropathy unresponsive to intravenous immunoglobulins: results of a retrospective study
by: Yann Péréon, et al.
Published: (2025-03-01)

Chronic inflammatory demyelinating polyneuropathy following COVID-19 vaccination: a case report and literature review
by: Mohammad Ali Bahramy, et al.
Published: (2024-07-01)

Electrophysiological assessment of Chronic Inflammatory Demyelinating Peripheral Polyradiculoneuropathy(CIDP) in Patients with Diabetes Mellitus
by: Marwa S. Suhail, et al.
Published: (2014-10-01)

Fungal Gut Microbiome in Myasthenia Gravis: A Sub-Analysis of the MYBIOM Study
by: Hedda Luise Verhasselt, et al.
Published: (2023-05-01)