Phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application
The paradigm of using phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application has been well established over the past decade. Phenylboronic acid and its derivatives are known to form reversible complexes with polyols, including sugar, diol and diphenol. This unique chemistr...
| Published in: | Nanotechnology Reviews |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2019-12-01
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| Subjects: | |
| Online Access: | https://doi.org/10.1515/ntrev-2019-0049 |
| _version_ | 1852766069676048384 |
|---|---|
| author | Lan Tianyu Guo Qianqian |
| author_facet | Lan Tianyu Guo Qianqian |
| author_sort | Lan Tianyu |
| collection | DOAJ |
| container_title | Nanotechnology Reviews |
| description | The paradigm of using phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application has been well established over the past decade. Phenylboronic acid and its derivatives are known to form reversible complexes with polyols, including sugar, diol and diphenol. This unique chemistry of phenylboronic acid has given many chances to be exploited for diagnostic and therapeutic applications. This review highlights the recent advances in fabrication of phenylboronic acid-decorated polymeric nanomaterials, especially focus on the interactions with glucose and sialic acid. Applications of these phenylboronic acid-decorated nanomaterials in drug delivery systems and biosensors are discussed. |
| format | Article |
| id | doaj-art-9e6d00f7bcac4cd9a178ca5fe4c26331 |
| institution | Directory of Open Access Journals |
| issn | 2191-9097 |
| language | English |
| publishDate | 2019-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| spelling | doaj-art-9e6d00f7bcac4cd9a178ca5fe4c263312025-08-19T20:53:44ZengDe GruyterNanotechnology Reviews2191-90972019-12-018154856110.1515/ntrev-2019-0049Phenylboronic acid-decorated polymeric nanomaterials for advanced bio-applicationLan Tianyu0Guo Qianqian1School of Chemical Engineering, Guizhou Minzu University, Guiyang 550025, Guizhou Province, ChinaDepartment of pharmaceutical Engineering (State Key Laboratory of Functions and Applications of Medicinal Plants, the Key Laboratory of Optimal Utilization of Natural Medicine Resources), School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang, Guizhou 550025, ChinaThe paradigm of using phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application has been well established over the past decade. Phenylboronic acid and its derivatives are known to form reversible complexes with polyols, including sugar, diol and diphenol. This unique chemistry of phenylboronic acid has given many chances to be exploited for diagnostic and therapeutic applications. This review highlights the recent advances in fabrication of phenylboronic acid-decorated polymeric nanomaterials, especially focus on the interactions with glucose and sialic acid. Applications of these phenylboronic acid-decorated nanomaterials in drug delivery systems and biosensors are discussed.https://doi.org/10.1515/ntrev-2019-0049phenylboronic acidpolymeric nanomaterialspolyolsdrug delivery |
| spellingShingle | Lan Tianyu Guo Qianqian Phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application phenylboronic acid polymeric nanomaterials polyols drug delivery |
| title | Phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application |
| title_full | Phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application |
| title_fullStr | Phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application |
| title_full_unstemmed | Phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application |
| title_short | Phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application |
| title_sort | phenylboronic acid decorated polymeric nanomaterials for advanced bio application |
| topic | phenylboronic acid polymeric nanomaterials polyols drug delivery |
| url | https://doi.org/10.1515/ntrev-2019-0049 |
| work_keys_str_mv | AT lantianyu phenylboronicaciddecoratedpolymericnanomaterialsforadvancedbioapplication AT guoqianqian phenylboronicaciddecoratedpolymericnanomaterialsforadvancedbioapplication |