Cognitive benefits of folic acid supplementation during pregnancy track with epigenetic changes at an imprint regulator
Abstract Background The human ZFP57 gene is a major regulator of imprinted genes, maintaining DNA methylation marks that distinguish parent-of-origin-specific alleles. DNA methylation of the gene itself has shown sensitivity to environmental stimuli, particularly folate status. However, the role of...
| 發表在: | BMC Medicine |
|---|---|
| Main Authors: | L. Hilman, M. Ondičová, A. Caffrey, M. Clements, C. Conway, M. Ward, K. Pentieva, R. E. Irwin, H. McNulty, C. P. Walsh |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
BMC
2024-12-01
|
| 主題: | |
| 在線閱讀: | https://doi.org/10.1186/s12916-024-03804-2 |
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