Viral hijacking of a replicative helicase loader and its implications for helicase loading control and phage replication
Replisome assembly requires the loading of replicative hexameric helicases onto origins by AAA+ ATPases. How loader activity is appropriately controlled remains unclear. Here, we use structural and biochemical analyses to establish how an antimicrobial phage protein interferes with the function of t...
| 發表在: | eLife |
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| Main Authors: | , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
eLife Sciences Publications Ltd
2016-05-01
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| 主題: | |
| 在線閱讀: | https://elifesciences.org/articles/14158 |