Neutrophil/Lymphocyte Ratio as a Biomarker of Response to H1-Antihistamine Therapy in Patients with Chronic Spontaneous Urticaria

Backgrounds A large proportion of patients with chronic spontaneous urticaria (CSU) are resistant to a standard dose of antihistamine. Acknowledged biomarkers for identifying these patients have not been determined. The neutrophil/lymphocyte ratio (NLR) has been considered as an important indicator...

Full description

Bibliographic Details
Published in:	Indian Journal of Dermatology
Main Authors:	Xiaonan Qiu, Qiao Ran, Juanjuan Pan, Guozhen Tan
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2024-11-01
Subjects:	biomarker csu h1-antihistamine refractory neutrophil/lymphocyte ratio
Online Access:	https://journals.lww.com/10.4103/ijd.ijd_558_22

Similar Items

Evaluation of New Inflammatory Parameters in Patients With Chronic Spontaneous Urticaria: A New Predictor of Refractoriness to Antihistamine Treatment
by: Nur Cihan COSANSU
Published: (2020-12-01)

The Predictive Value of Serum Total IgE for Antihistamine Treatment Outcomes in Chinese Patients with Chronic Spontaneous Urticaria
by: Yingyi Li, et al.
Published: (2025-08-01)

Platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio as predictors of refractory anaphylaxis
by: Le Vinh Nghi, MD, et al.
Published: (2024-08-01)

ANTIHISTAMINES IN TREATMENT OF CHRONIC URTICARIA. REVIEW OF MODERN RECOMMENDATIONS
by: M. V. LEONOVA, et al.
Published: (2016-12-01)

Increased Neutrophil–Lymphocyte Ratio and Platelet–Lymphocyte Ratio in Chronic and Severe Urticaria
by: Sarah Weissmann, et al.
Published: (2024-04-01)

Effectiveness and safety of new-generation antihistamines in allergenic rhinitis and urticaria
by: P.C. Potter
Published: (2005-08-01)

Current and Emerging Therapies for Chronic Spontaneous Urticaria: A Narrative Review
by: Gil Yosipovitch, et al.
Published: (2023-06-01)

Pathobiology of Second-Generation Antihistamines Related to Sleep in Urticaria Patients
by: Caroline Mann, et al.
Published: (2022-03-01)

Eosinophilic cationic protein and D-Dimer are potential biomarkers to predict response to antihistamines but not to omalizumab in chronic spontaneous urticaria
by: Özge Atik, et al.
Published: (2024-12-01)

Antihistamines in Pregnancy
by: Javad Ghaffari
Published: (2023-10-01)

Evidence Gaps in Clinical Trials of Pharmacologic Treatment for H1-Antihistamine-Refractory Chronic Spontaneous Urticaria: A Systematic Review and Future Perspectives
by: Surapon Nochaiwong, et al.
Published: (2022-10-01)

Role of cyproheptadine in chronic urticaria not controlled with second-generation antihistamines: a retrospective study
by: Shambo S. Samajdar, et al.
Published: (2025-09-01)

Up-dosing of non-sedating antihistamines in chronic urticaria: Need for well-designed clinical trials in India
by: Anant D Patil
Published: (2014-01-01)

Selecting optimal second-generation antihistamines for allergic rhinitis and urticaria in Asia
by: Marysia Tiongco Recto, et al.
Published: (2017-11-01)

Improving of psychological status and inflammatory biomarkers during omalizumab for chronic spontaneous urticaria
by: Laura Diluvio, et al.
Published: (2020-10-01)

Disparities in chronic spontaneous urticaria: Eligibility for drug reimbursement associated with clinical outcomes
by: Hugo W.F. Mak, MBBS MRes(Med), et al.
Published: (2024-05-01)

Neutrophil Lymphocyte Ratio in Patients Receiving Isotretinoin for Acne Vulgaris
by: Arzu Ataseven, et al.
Published: (2014-03-01)

Serum MRGPRX2 and substance P levels are biomarkers of disease activity rather than an antihistamine response in chronic spontaneous urticaria
by: Nguyen Thi Kim Cuc, et al.
Published: (2025-03-01)

Allergic rhinitis and urticaria burden and antihistamine treatment options in Thailand: A modified Delphi study
by: Hiroshi Chantaphakul, MD, et al.
Published: (2025-05-01)

CD4+CCR5+ T cells and CCL3+ mast cells are increased in the skin of patients with chronic spontaneous urticaria
by: Raeda Mubariki, et al.
Published: (2024-07-01)

A Retrospective Evaluation of Mean Platelet Volume and the Neutrophil-to-lymphocyte Ratio in Children with Chronic Urticaria
by: Mehmet Ali Duman, et al.
Published: (2019-09-01)

Diagnostic Performance of Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio in Endometrioma
by: Derya Sivri Aydın
Published: (2019-01-01)

Neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and their association with the severity of depression and as biomarkers for suicidal behaviour among patients diagnosed with depression
by: Swathi, et al.
Published: (2023-10-01)

Neutrophil Lymphocyte Ratio as Screening Tool for Neonatal Sepsis in Developing Countries
by: Nauman Naseer, et al.
Published: (2023-05-01)

Phototherapy for Treating Chronic Spontaneous Urticaria
by: Zilpa Widyastuti, et al.
Published: (2025-07-01)

Dupilumab Reduces Urticaria Activity, Itch, and Hives in Patients with Chronic Spontaneous Urticaria Regardless of Baseline Serum Immunoglobulin E Levels
by: Marcus Maurer, et al.
Published: (2024-07-01)

Sleep Disturbance and Chronic Urticaria: A Narrative Review of Its Relationship, Treatment and Evolving Literature
by: Asad Ullah Wasim, et al.
Published: (2025-05-01)

The prevalence of patients suffering from chronic spontaneous urticaria, in whom omalizumab cannot be stopped even after six years
by: V. Schichter-Konfino, et al.
Published: (2024-10-01)

Are neutrophil-lymphocyte and platelet-lymphocyte ratios valuable in predicting prostate cancer?
by: Ahmet Camtosun, et al.
Published: (2016-12-01)

The neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and neutrophil-to-high-density-lipoprotein ratio are correlated with the severity of Parkinson’s disease
by: Fangyi Li, et al.
Published: (2024-01-01)

The Assessment of the Neutrophil-lymphocyte Ratio and Platelet-lymphocyte Ratio in Dyslipidemic Obese Children
by: Tuğçe Damla Dilek, et al.
Published: (2019-09-01)

Evaluation of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in chronic plaque psoriasis
by: Sudeshna Mondal, et al.
Published: (2022-01-01)

Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as predictive markers in hepatoblastoma
by: Tan Xie, et al.
Published: (2023-04-01)

Strongyloides infection as a reversible cause of chronic urticaria
by: Zubrinich CM, et al.
Published: (2019-02-01)

Neutrophil/lymphocyte ratio as serum inflammatory biomarker in patients with moderate-to-severe plaque psoriasis
by: Maria E. Agapito-Valgas, et al.
Published: (2023-04-01)

Role of Neutrophil Lymphocyte Ratio at Preoperative Adenomysosis Diagnosis
by: Mehmet Kececioglu, et al.
Published: (2016-06-01)

Neutrophil-to-Lymphocyte Ratio in Adult Patients with Anemia: A Hospital-Based Cross-Sectional Study
by: Nilu Manandhar, et al.
Published: (2023-12-01)

Can Neutrophil/Lymphocyte Ratio be Used as a New Biomarker in the Evaluation of Disease Activity in Children with Bronchiolitis?
by: Eda ÇELİK GÜZEL, et al.
Published: (2019-04-01)

Neutrophil and neutrophil-lymphocyte ratios as predictors of clinical characteristics in patients with Lymphangioleiomyomatosis
by: Lulu Yang, et al.
Published: (2025-06-01)

Management of Pediatric Chronic Spontaneous Urticaria: A Review of Current Evidence and Guidelines
by: Chang J, et al.
Published: (2021-03-01)