Photo‐Promoted Nitrogen‐Centered Radical Mediated Intermolecular Aminative Carbonylation of Tertiary Allyl Alcohols to Access β‐Amino Ketones through (Hetero)Aryl Migration

Abstract Carbon monoxide, as a crucial C1 synthon, has been widely used in the difunctionalization of alkenes. Additionally, nitrogen‐centered radicals (NCRs) are also effective intermediates for constructing C−N bonds. Herein, a nitrogen‐centered radical‐mediated aminative carbonylation strategy fo...

詳細記述

書誌詳細
出版年:ChemistryEurope
主要な著者: Ming Hou, Yuanrui Wang, Hefei Yang, Jiajun Zhang, Prof. Dr. Xiao‐Feng Wu
フォーマット: 論文
言語:英語
出版事項: Wiley-VCH 2025-05-01
主題:
nitrogen-centered radical
photocatalysis
unactivated alkenes
carbonylation
amination
オンライン･アクセス:https://doi.org/10.1002/ceur.202500001
その他の書誌記述
要約:Abstract Carbon monoxide, as a crucial C1 synthon, has been widely used in the difunctionalization of alkenes. Additionally, nitrogen‐centered radicals (NCRs) are also effective intermediates for constructing C−N bonds. Herein, a nitrogen‐centered radical‐mediated aminative carbonylation strategy for producing β‐amino ketones from tertiary allyl alcohols has been disclosed. Good yields of β‐amino ketones with different functional groups were generated effectively under light irradiation.
ISSN:2751-4765

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