Penetrating Keratoplasty after Radial Keratotomy and Recurrent Immune Overreaction

A 32-year-old man suffering from keratoconus was treated with radial keratotomy. Twenty weeks later, he presented visual deterioration, edema and corneal perforation. A penetrating keratoplasty was required. The postoperative course was regular, but after 9 months, the patient presented kerato-uveit...

詳細記述

書誌詳細
出版年:Case Reports in Ophthalmology
主要な著者: Raffaele Nuzzi, Elisa Buschini
フォーマット: 論文
言語:英語
出版事項: Karger Publishers 2011-04-01
主題:
オンライン・アクセス:http://www.karger.com/Article/FullText/324750
その他の書誌記述
要約:A 32-year-old man suffering from keratoconus was treated with radial keratotomy. Twenty weeks later, he presented visual deterioration, edema and corneal perforation. A penetrating keratoplasty was required. The postoperative course was regular, but after 9 months, the patient presented kerato-uveitis. Subsequent phlogistic relapses occurred approximately every 6 months during the following 5 years. The performed cultures were positive only during the first episode. Radial keratotomy is not indicated in keratoconus. The multiple relapses of kerato-uveitis could not be explained by infection, and we hypothesized that they may be due to a ‘traumatic memory’ of the cornea caused by the several suffered traumatisms, without clinical features of corneal graft rejection. The risks of new penetrating keratoplasty and cataract surgery are high. As the cornea is the tissue with the highest sensitivity in the body, we tried to explain the relapsing kerato-uveitis as a consequence of the disruption of the nervous corneal network.
ISSN:1663-2699