Early response evaluation by single cell signaling profiling in acute myeloid leukemia

The molecular mechanisms underlying response to chemotherapy in Acute myeloid leukemia (AML) remain to be explored. Here, the authors perform 36-dimensional mass cytometry in 32 AML patients during intensive chemotherapy and suggest functional signalling analysis for prognosis prediction early after...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Benedicte Sjo Tislevoll, Monica Hellesøy, Oda Helen Eck Fagerholt, Stein-Erik Gullaksen, Aashish Srivastava, Even Birkeland, Dimitrios Kleftogiannis, Pilar Ayuda-Durán, Laure Piechaczyk, Dagim Shiferaw Tadele, Jørn Skavland, Panagotis Baliakas, Randi Hovland, Vibeke Andresen, Ole Morten Seternes, Tor Henrik Anderson Tvedt, Nima Aghaeepour, Sonia Gavasso, Kimmo Porkka, Inge Jonassen, Yngvar Fløisand, Jorrit Enserink, Nello Blaser, Bjørn Tore Gjertsen
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Online Access:https://doi.org/10.1038/s41467-022-35624-4
Description
Summary:The molecular mechanisms underlying response to chemotherapy in Acute myeloid leukemia (AML) remain to be explored. Here, the authors perform 36-dimensional mass cytometry in 32 AML patients during intensive chemotherapy and suggest functional signalling analysis for prognosis prediction early after treatment in AML.
ISSN:2041-1723

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