The Paradoxical Association of Lipids with Survival and Walking Ability of Hip Fractures in Geriatric Patients After Surgery: A 1-Year Follow-Up Study

• الحاوية / القاعدة: International Journal of General Medicine
• المؤلفون الرئيسيون: Zhao Z, Fan W, Wang L, Chu Q
• التنسيق: مقال
• اللغة: الإنجليزية
• منشور في: Dove Medical Press 2023-08-01
• الموضوعات: hip fractures; ldl-c; lipid; dyslipidemia; prognosis
• الوصول للمادة أونلاين: https://www.dovepress.com/the-paradoxical-association-of-lipids-with-survival-and-walking-abilit-peer-reviewed-fulltext-article-IJGM

Zhibang Zhao, Wenliang Fan, Liqiang Wang, Qingbo Chu Emergency Trauma Center, Nanyang Second People’s Hospital, Nanyang, Henan, People’s Republic of ChinaCorrespondence: Qingbo Chu, Emergency Trauma Center, Nanyang Second People’s Hospital, No. 66 East Jianshe Road, Nanyang, Henan, 473000, People’s Republic of China, Email [e-mail]: We aimed to explore the association between lipids and the survival and walking ability of hip fractures in geriatric patients after surgery.Methods: Restricted cubic spline (RCS) was established to explore the nonlinear relationship between lipids and 1-year mortality of hip fractures, and the cut-off points were also determined by RCS. Then, the patients were divided into three groups: low, middle, and high levels of LDL-c. Then, the survival and walking ability of patients from different groups were compared, and the Cox regression and Logistics regression were used to identify the relationships between lipids and the survival and walking ability of hip fractures.Results: The patients with middle levels of LDL-c had a significantly high survival probability than those with low or high levels of LDL-c (p < 0.001). The patients with low levels of LDL-c and with high levels of LDL-c may have a poor prognosis compared with patients with middle levels of LDL-c in 6-month mortality, 6-month free walking ability, 1-year mortality, and 1-year free walking ability (All p < 0.05).Conclusion: Low and high levels of LDL-c may both relate to the poor survival and walking ability of hip fractures.Keywords: hip fractures, LDL-c, lipid, dyslipidemia, prognosis