An intracellular phosphorus-starvation signal activates the PhoB/PhoR two-component system in Salmonella enterica

ABSTRACT Bacteria acquire P primarily as inorganic orthophosphate (Pi, PO43−). Once internalized, Pi is rapidly assimilated into biomass during the synthesis of ATP. Because Pi is essential, but excessive ATP is toxic, the acquisition of environmental Pi is tightly regulated. In the bacterium Salmon...

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