Distinguishing Crohn’s Disease From Non–Crohn’s Ileitis: A Gut Microbiome–Based Approach

Conclusion: The gut microbiome is unique in NCI and can be differentiated from Crohn’s by a novel bacterial profile. This study provides preliminary leads to help stratify patients who require active treatment in lines of CD.

Bibliographic Details
Published in:	Advanced Gut & Microbiome Research
Main Authors:	Nalini Raghunathan, Varun Joshi, Dhanush Mekala, Rajendra Patel, Shubhankar Godbole, Rupjyoti Talukdar, Duvvur Nageshwar Reddy, Rupa Banerjee
Format:	Article
Language:	English
Published:	Wiley 2025-01-01
Online Access:	http://dx.doi.org/10.1155/agm3/8253763

Similar Items

A case of terminal ileitis that was not Crohn’s disease
by: H. M. Dmytriakova, et al.
Published: (2022-11-01)

Management of Pancreatic Calculi: An Update
by: Manu Tandan, et al.
Published: (2016-11-01)

CMV Ileitis: To Treat or Not to Treat? Implications of Initiating Biologic Therapy for Concurrent Crohn’s Disease
by: Kendra T. Stilwell, et al.
Published: (2019-01-01)

Entamoeba histolytica‐associated proctitis and ileitis mimicking Crohn's disease—A case report
by: Thomas Griemert, et al.
Published: (2023-05-01)

The Revival of Surgery in Crohn’s Disease—Early Intestinal Resection as a Reasonable Alternative in Localized Ileitis
by: Matthias Kelm, et al.
Published: (2021-09-01)

Crohn′s Ileiti′s presenting with massive gastrointestinal hemorrhage - case report and review of literature
by: Rahmatulla Rehan, et al.
Published: (2000-01-01)

Endoscopic Evaluation and Therapeutic Considerations of Small Bowel Crohn’s Disease
by: Rupa Banerjee, et al.
Published: (2021-05-01)

Why Distinguish between Ulcerative Colitis and Crohn’s Disease?
by: Daniel Rachmilewitz
Published: (1989-01-01)

Proposal of novel staging system CNM (Crohn’s primary site, nodes, mesentery) to predict postoperative recurrence of Crohn’s disease
by: Guduru Venkat Rao, et al.
Published: (2023-04-01)

Long-Term Environmental Hypoxia Exposure and Haematopoietic Prolyl Hydroxylase-1 Deletion Do Not Impact Experimental Crohn’s Like Ileitis
by: Cara De Galan, et al.
Published: (2021-09-01)

COVID-19 vaccination-infection status and immunological profile from India: A case study for prioritizing at risk population for targeted immunization
by: Deepika Gujjarlapudi, et al.
Published: (2025-07-01)

Laparoscopic ileocolic resection versus infliximab treatment of distal ileitis in Crohn's disease: a randomized multicenter trial (LIR!C-trial)
by: van Heukelem Henk A, et al.
Published: (2008-08-01)

Schistosoma mansoni Coinfection Attenuates Murine Toxoplasma gondii-Induced Crohn's-Like Ileitis by Preserving the Epithelial Barrier and Downregulating the Inflammatory Response
by: Beatriz Pêgo, et al.
Published: (2019-03-01)

Distinguishing between Crohn′s disease, tuberculosis, and lymphoma: Still in murky waters
by: Majid A Almadi
Published: (2014-01-01)

A Diet Fortified with Anthocyanin-Rich Extract (RED) Reduces Ileal Inflammation in a Senescence-Prone Mice Model of Crohn’s-Disease-like Ileitis
by: Giulio Verna, et al.
Published: (2025-04-01)

Crohn's disease or histoplasmosis? A case of severe disseminated histoplasmosis mimicking Crohn's disease and literature review
by: Ahmed Ahmed, et al.
Published: (2020-12-01)

Diagnosis of Crohn’s disease and ulcerative colitis using the microbiome
by: Da-Yeon Kang, et al.
Published: (2023-11-01)

The microbiome landscape in pediatric Crohn’s disease and therapeutic implications
by: Karin Fetter, et al.
Published: (2023-12-01)

Endoscopic Management of Pancreatic Fluid Collections in Children
by: Zaheer Nabi, et al.
Published: (2017-07-01)

RIPK2 Inhibition Blocks NOD2-Mediated IL-1β Production by Macrophages In Vitro but Exacerbates Crohn’s Disease-like Ileitis in SHIP–/– Mice
by: Yvonne C. F. Pang, et al.
Published: (2025-08-01)

Laparoscopic bowel resection combined with infliximab treatment (LaRIC) versus infliximab for terminal ileitis in Crohn’s disease: a randomised, controlled, open-label trial
by: Yang Yang, et al.
Published: (2020-11-01)

Mucosal microbiome of surgically treated terminal ileal Crohn’s disease
by: Florian N. Loch, et al.
Published: (2024-01-01)

Characterization of the Mucosally-Adherent Duodenal Microbiome in Children with and without Crohn’s Disease
by: Kenneth Schmidt, et al.
Published: (2022-07-01)

Comparative diet-gut microbiome analysis in Crohn’s disease and Hidradenitis suppurativa
by: Peter Cronin, et al.
Published: (2023-11-01)

Progress and Clinical Applications of Crohn’s Disease Exclusion Diet in Crohn’s Disease
by: Duo Xu, et al.
Published: (2024-05-01)

Short versus long esophageal myotomy during peroral endoscopic myotomy: A systematic review and meta-analysis of comparative trials
by: Zaheer Nabi, et al.
Published: (2022-01-01)

Endoscopic Fistulotomy (through the Scope and Freehand) as a Salvage Procedure for Recurrent Perianal Fistula with Abscess Postsurgery in Crohn's Disease
by: Partha Pal, et al.
Published: (2024-12-01)

Immunotherapy of Crohn's disease
by: C. van Montfrans, et al.
Published: (1998-01-01)

Crohn’s Disease and Cheilitis
by: Abdulrahman A Al-Hussaini, et al.
Published: (2003-01-01)

Granulomatous (Crohn’s) Appendicitis
by: Hanna Binder, et al.
Published: (1991-01-01)

Recurrence in Crohn’s Disease
by: Adrian J Greenstein
Published: (1993-01-01)

Management of Crohn’s Disease
by: MRB Keighley
Published: (1993-01-01)

Appendectomy and Crohn's Disease
by: Ana Catarina Caetano Fonseca Loureiro, et al.
Published: (2019-10-01)

Urolithiasis and crohn's disease
by: Sandro Roberto da Silva Gaspar, et al.
Published: (2016-01-01)

Enterotomografía en la enfermedad de Crohn CT enterography in Crohn's disease
by: María Alejandra Lalanne, et al.
Published: (2012-09-01)

Motorized spiral enteroscope-assisted retrieval of video capsule in a patient with Crohn’s disease
by: Pradev Inavolu, MD, DM, et al.
Published: (2020-10-01)

Profiles and interactions of gut microbiome and intestinal microRNAs in pediatric Crohn’s disease
by: Yao Lv, et al.
Published: (2024-09-01)

Multimodal Ultrasound-Guided Hybrid Endoscopic Therapy Averting Pouch Excision and Permanent Stoma in Crohn's Disease of the Pouch
by: Partha Pal, et al.

Endoscopic Setons Placement for Complex Perianal Fistulizing Crohn's Disease by Fistuloscopy Using Ultra-thin Endoscope Introduced into Fistula Cavity
by: Partha Pal, et al.
Published: (2023-12-01)

Freehand Endoscopic Fistulotomy Guided by Perineal Ultrasound in Crohn's Perianal Abscess: A Day-Care Alternative to Surgery Allowing Continuation of Biologics
by: Partha Pal, et al.