A hyper-acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab: a case report

Contrast medium is frequently associated with allergic reactions and kidney dysfunction. However, contrast media can induce hemolytic anemia with a broad spectrum of hemolytic manifestations. We report a 38-year-old patient with very severe immune hemolytic anemia after the application of iomeprol d...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Frontiers in Immunology
المؤلفون الرئيسيون: Sabine Hermann, Karina Althaus, Migdat Mustafi, Beate Mayer, Peter Rosenberger, Helene Anna Haeberle, Alice Bernard
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Frontiers Media S.A. 2025-02-01
الموضوعات:
drug-induced hemolysis
contrast medium-induced hemolysis
eculizumab
hemolytic anemia
immunological hemolysis
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1464014/full
الوصف
الملخص:Contrast medium is frequently associated with allergic reactions and kidney dysfunction. However, contrast media can induce hemolytic anemia with a broad spectrum of hemolytic manifestations. We report a 38-year-old patient with very severe immune hemolytic anemia after the application of iomeprol due to a CT of the thorax/abdomen. In this case report, we illustrate the diagnostics and treatment of life-threatening hemolytic anemia induced by a contrast medium that was successfully treated with eculizumab.
تدمد:1664-3224

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