Research on liver cancer segmentation method based on PCNN image processing and SE-ResUnet

Abstract As one of the malignant tumors with high mortality, the initial symptoms of liver cancer are not obvious. In addition, the liver is the largest internal organ of the human body, and its structure and distribution are relatively complex. Therefore, in order to help doctors judge liver cancer...

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Published in:Scientific Reports
Main Authors: Lan Zang, Wei Liang, Hanchu Ke, Feng Chen, Chong Shen
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Online Access:https://doi.org/10.1038/s41598-023-39240-0
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author Lan Zang
Wei Liang
Hanchu Ke
Feng Chen
Chong Shen
author_facet Lan Zang
Wei Liang
Hanchu Ke
Feng Chen
Chong Shen
author_sort Lan Zang
collection DOAJ
container_title Scientific Reports
description Abstract As one of the malignant tumors with high mortality, the initial symptoms of liver cancer are not obvious. In addition, the liver is the largest internal organ of the human body, and its structure and distribution are relatively complex. Therefore, in order to help doctors judge liver cancer more accurately, this paper proposes a variant model based on Unet network. Before segmentation, the image is preprocessed, and Pulse Coupled Neural Network (PCNN) algorithm is used to filter the image adaptively to make the image clearer. For the segmentation model, the SE module is used as the input of the residual network, and then its output is connected to the Unet model through bilinear interpolation to perform the down-sampling and up-sampling operations. The dataset is a combination of Hainan Provincial People's Hospital and some public datasets Lits. The results show that this method has better segmentation performance and accuracy than the original Unet method, and the dice coefficient, mIou and other evaluation indicators have increased by at least 2.1%, which is a method that can be applied to cancer segmentation.
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spelling doaj-art-a4b98a77fa3e4d0e87deec0a9bef646e2025-08-20T01:10:25ZengNature PortfolioScientific Reports2045-23222023-08-0113111410.1038/s41598-023-39240-0Research on liver cancer segmentation method based on PCNN image processing and SE-ResUnetLan Zang0Wei Liang1Hanchu Ke2Feng Chen3Chong Shen4State Key Laboratory of Marine Resource Utilization in South China Sea, Hainan UniversityState Key Laboratory of Marine Resource Utilization in South China Sea, Hainan UniversitySchool of Electronic Science and Technology, Hainan UniversityDepartment of Radiology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University)State Key Laboratory of Marine Resource Utilization in South China Sea, Hainan UniversityAbstract As one of the malignant tumors with high mortality, the initial symptoms of liver cancer are not obvious. In addition, the liver is the largest internal organ of the human body, and its structure and distribution are relatively complex. Therefore, in order to help doctors judge liver cancer more accurately, this paper proposes a variant model based on Unet network. Before segmentation, the image is preprocessed, and Pulse Coupled Neural Network (PCNN) algorithm is used to filter the image adaptively to make the image clearer. For the segmentation model, the SE module is used as the input of the residual network, and then its output is connected to the Unet model through bilinear interpolation to perform the down-sampling and up-sampling operations. The dataset is a combination of Hainan Provincial People's Hospital and some public datasets Lits. The results show that this method has better segmentation performance and accuracy than the original Unet method, and the dice coefficient, mIou and other evaluation indicators have increased by at least 2.1%, which is a method that can be applied to cancer segmentation.https://doi.org/10.1038/s41598-023-39240-0
spellingShingle Lan Zang
Wei Liang
Hanchu Ke
Feng Chen
Chong Shen
Research on liver cancer segmentation method based on PCNN image processing and SE-ResUnet
title Research on liver cancer segmentation method based on PCNN image processing and SE-ResUnet
title_full Research on liver cancer segmentation method based on PCNN image processing and SE-ResUnet
title_fullStr Research on liver cancer segmentation method based on PCNN image processing and SE-ResUnet
title_full_unstemmed Research on liver cancer segmentation method based on PCNN image processing and SE-ResUnet
title_short Research on liver cancer segmentation method based on PCNN image processing and SE-ResUnet
title_sort research on liver cancer segmentation method based on pcnn image processing and se resunet
url https://doi.org/10.1038/s41598-023-39240-0
work_keys_str_mv AT lanzang researchonlivercancersegmentationmethodbasedonpcnnimageprocessingandseresunet
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AT hanchuke researchonlivercancersegmentationmethodbasedonpcnnimageprocessingandseresunet
AT fengchen researchonlivercancersegmentationmethodbasedonpcnnimageprocessingandseresunet
AT chongshen researchonlivercancersegmentationmethodbasedonpcnnimageprocessingandseresunet