Expression of Heat Shock Protein 70 Modulates the Chemoresponsiveness of Pancreatic Cancer
Background/AimsHeat shock protein (HSP) 70 is constitutively overexpressed in pancreatic cancer cells (PCCs) and appears to confer protection against chemotherapeutics. We investigated whether modulating HSP 70 increases chemoresponsiveness to gemcitabine in PCCs.Methods : Varying concentrations of...
| Published in: | Gut and Liver |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Gastroenterology Council for Gut and Liver
2013-11-01
|
| Subjects: | |
| Online Access: | http://gutnliver.org/journal/view.html?doi=10.5009/gnl.2013.7.6.739 |
Similar Items
Heat Shock Proteins and Autophagy in Rats with Cerulein-Induced Acute Pancreatitis
Published: (2011-12-01)
Published: (2011-12-01)
Heat Shock Proteins in Pancreatic Cancer: Pathogenic Mechanisms and Clinical Implications
by: Jacek Kabut, et al.
Published: (2025-10-01)
by: Jacek Kabut, et al.
Published: (2025-10-01)
Phase II Trial of Erlotinib Plus Gemcitabine Chemotherapy in Korean Patients with Advanced Pancreatic Cancer and Prognostic Factors for Chemotherapeutic Response
Published: (2013-09-01)
Published: (2013-09-01)
The Role of the Heat-Shock Proteins in Esophagogastric Cancer
by: Francisco Tustumi, et al.
Published: (2022-08-01)
by: Francisco Tustumi, et al.
Published: (2022-08-01)
Evaluation of serum levels of heat shock protein 70 in patients with psoriasis in Basra, Iraq
by: Wafaa Taresh Adday, et al.
Published: (2024-07-01)
by: Wafaa Taresh Adday, et al.
Published: (2024-07-01)
Systemic Chemotherapy in Advanced Pancreatic Cancer
by: Hee Seung Lee, et al.
Published: (2016-05-01)
by: Hee Seung Lee, et al.
Published: (2016-05-01)
Synergistic Effect of Quercetin and Cobalt Ferrite-Graphene Oxide-Based Hyperthermia to Inhibit Expression of Heat Shock Proteins and Induce Apoptosis in Breast Cancer Cells
by: Fatemeh Mobaraki, et al.
Published: (2022-10-01)
by: Fatemeh Mobaraki, et al.
Published: (2022-10-01)
Comparative modeling and mutual docking of structurally uncharacterized heat shock protein 70 and heat shock factor-1 proteins in water buffalo
by: Ravinder Singh, et al.
Published: (2019-12-01)
by: Ravinder Singh, et al.
Published: (2019-12-01)
Discovering a Reliable Heat-Shock Factor-1 Inhibitor to Treat Human Cancers: Potential Opportunity for Phytochemists
by: Murugesan Velayutham, et al.
Published: (2018-04-01)
by: Murugesan Velayutham, et al.
Published: (2018-04-01)
Bladder cancer microbiome and its association with chemoresponse
by: Rashida Ginwala, et al.
Published: (2025-07-01)
by: Rashida Ginwala, et al.
Published: (2025-07-01)
Gemcitabine-Induced Hemolytic Uremic Syndrome in Pancreatic Cancer: A Case Report and Review of the Literature
Published: (2014-01-01)
Published: (2014-01-01)
Modified gemcitabine plus nab‐paclitaxel regimen in advanced pancreatic ductal adenocarcinoma
by: Jane E. Rogers, et al.
Published: (2020-08-01)
by: Jane E. Rogers, et al.
Published: (2020-08-01)
The relationship of Heat Shock Protein-70(HSP-70) and toxoplasmosis among women with abortion
by: Kareem Mohammed, et al.
Published: (2012-08-01)
by: Kareem Mohammed, et al.
Published: (2012-08-01)
Efficacy of Nab-Paclitaxel Plus Gemcitabine and Prognostic Value of Peripheral Neuropathy in Patients with Metastatic Pancreatic Cancer
by: Min Su You, et al.
Published: (2018-11-01)
by: Min Su You, et al.
Published: (2018-11-01)
Heat shock proteins: a therapeutic target worth to consider
by: Amita Dubey, et al.
Published: (2015-01-01)
by: Amita Dubey, et al.
Published: (2015-01-01)
Heat shock factor 1 inhibits the mitochondrial apoptosis pathway by regulating second mitochondria-derived activator of caspase to promote pancreatic tumorigenesis
by: Wenjin Liang, et al.
Published: (2017-05-01)
by: Wenjin Liang, et al.
Published: (2017-05-01)
Heat Shock Protein 70 and 90 Family in Prostate Cancer
by: Xun Fu, et al.
Published: (2022-09-01)
by: Xun Fu, et al.
Published: (2022-09-01)
The Expression of and Preoperative Correlation between Heat-Shock Protein 70, EuroSCORE, and Lactate in Patients undergoing CABG with Cardiopulmonary Bypass
by: Marcos Antonio Cantero, et al.
by: Marcos Antonio Cantero, et al.
Involvement of heat shock proteins HSP70 in the mechanisms of endogenous neuroprotection: the prospect of using HSP70 modulators
by: Igor F. Belenichev, et al.
Published: (2023-04-01)
by: Igor F. Belenichev, et al.
Published: (2023-04-01)
Effect of Trehalose on the Expression of Heat Shock Protein 70 Gene in PC12 Cells Treated with Hydrogen Peroxide
by: Mahdieh Nazari Robati, et al.
Published: (2019-05-01)
by: Mahdieh Nazari Robati, et al.
Published: (2019-05-01)
Second-line Modified GTX versus Gemcitabine-Nab-Paclitaxel (GmAb) Following First-Line FOLFIRINOX in Advanced Pancreatic Cancer: A Retrospective Analysis at the American University of Beirut Medical Center (AUBMC)
by: Sally Temraz, et al.
Published: (2023-10-01)
by: Sally Temraz, et al.
Published: (2023-10-01)
Heat shock proteins and oral diseases
by: G Suresh Babu, et al.
Published: (2012-01-01)
by: G Suresh Babu, et al.
Published: (2012-01-01)
Isolation and Characterization of Heat Shock Protein 70-Ipek 1 from Toxoplasma gondii
by: Kübra Açıkalın Coşkun, et al.
Published: (2024-09-01)
by: Kübra Açıkalın Coşkun, et al.
Published: (2024-09-01)
Expression Level of Heat Shock Protein in Blackgram under Elevated Heat Stress
by: C. Partheeban, et al.
Published: (2023-05-01)
by: C. Partheeban, et al.
Published: (2023-05-01)
Heat shock protein-70 is elevated in childhood primary immune thrombocytopenia
by: Jiao Ge, et al.
Published: (2022-11-01)
by: Jiao Ge, et al.
Published: (2022-11-01)
Heat shock protein 70 biomarkers in sperm and its association on oligoasthenozoospermia, and asthenozoospermia in male infertility
by: Ahmed Saidi Abdel Jail, et al.
Published: (2023-01-01)
by: Ahmed Saidi Abdel Jail, et al.
Published: (2023-01-01)
Influence of Dietary Energy Level on Hepatic70-kDa Heat Shock Protein Expression in Broiler Chickens Submitted to Acute Heat Stress
by: JE Gabriel, et al.
Published: (2000-09-01)
by: JE Gabriel, et al.
Published: (2000-09-01)
Heat Shock Protein 70 (HSP70) Induction: Chaperonotherapy for Neuroprotection after Brain Injury
by: Jong Youl Kim, et al.
Published: (2020-09-01)
by: Jong Youl Kim, et al.
Published: (2020-09-01)
Role of heat shock factor 1 in nab-paclitaxel sensitization in pancreatic ductal adenocarcinoma
by: Ahmad Hegazi, et al.
Published: (2025-10-01)
by: Ahmad Hegazi, et al.
Published: (2025-10-01)
Role of heat shock factor 1 in nab-paclitaxel sensitization in pancreatic ductal adenocarcinoma
by: Ahmad Hegazi, et al.
Published: (2025-10-01)
by: Ahmad Hegazi, et al.
Published: (2025-10-01)
Vitexin Regulates Heat Shock Protein Expression by Modulating ROS Levels Thereby Protecting against Heat-Stress-Induced Apoptosis
by: Tong Wu, et al.
Published: (2023-11-01)
by: Tong Wu, et al.
Published: (2023-11-01)
Maternal and Umbilical Cord Heat-Shock Protein 70 Levels in Patients with Gestational Diabetes Mellitus
by: Aybike Tazegul, et al.
Published: (2024-04-01)
by: Aybike Tazegul, et al.
Published: (2024-04-01)
Antioxidant capacity of five microalgae species and their effect on heat shock protein 70 expression in the brine shrimp Artemia
by: Irene Kai Ru Tiong, et al.
Published: (2020-11-01)
by: Irene Kai Ru Tiong, et al.
Published: (2020-11-01)
Interaction model between quercetin (3,5,7,3p,4p-pentahidroxiflavone) and human shock thermic factor (HFS)
by: Diana Carolina Clavijo B., et al.
Published: (2017-09-01)
by: Diana Carolina Clavijo B., et al.
Published: (2017-09-01)
THE ROLE OF THE HEAT SHOCK PROTEIN 70 IN THE PATHOGENESIS OF CARDIOVASCULAR PATHOLOGY
by: O. A. Ponasenko, et al.
Published: (2019-05-01)
by: O. A. Ponasenko, et al.
Published: (2019-05-01)
Detection of autoantibodies to heat shock protein 70 in the saliva and urine of normal individuals
by: Krzysztof Sitko, et al.
Published: (2024-07-01)
by: Krzysztof Sitko, et al.
Published: (2024-07-01)
Heat Shock Protein 70 Family in Response to Multiple Abiotic Stresses in the Silkworm
by: Shou-Min Fang, et al.
Published: (2021-10-01)
by: Shou-Min Fang, et al.
Published: (2021-10-01)
Heat Shock Proteins (HSPs) Inducers for Stress Management in Agricultural Crops
by: Shivendu Pratap Singh Solanki, et al.
Published: (2015-11-01)
by: Shivendu Pratap Singh Solanki, et al.
Published: (2015-11-01)
Improved Antitumor Efficiency of N4-Tetradecyloxycarbonyl Gemcitabine-Loaded Liposomes for Pancreatic Cancer Chemotherapy
by: Wang D, et al.
Published: (2024-12-01)
by: Wang D, et al.
Published: (2024-12-01)
Novel Use of Hypoxia-Inducible Polymerizable Protein to Augment Chemotherapy for Pancreatic Cancer
by: Andrew Gdowski, et al.
Published: (2022-01-01)
by: Andrew Gdowski, et al.
Published: (2022-01-01)
Similar Items
-
Heat Shock Proteins and Autophagy in Rats with Cerulein-Induced Acute Pancreatitis
Published: (2011-12-01) -
Heat Shock Proteins in Pancreatic Cancer: Pathogenic Mechanisms and Clinical Implications
by: Jacek Kabut, et al.
Published: (2025-10-01) -
Phase II Trial of Erlotinib Plus Gemcitabine Chemotherapy in Korean Patients with Advanced Pancreatic Cancer and Prognostic Factors for Chemotherapeutic Response
Published: (2013-09-01) -
The Role of the Heat-Shock Proteins in Esophagogastric Cancer
by: Francisco Tustumi, et al.
Published: (2022-08-01) -
Evaluation of serum levels of heat shock protein 70 in patients with psoriasis in Basra, Iraq
by: Wafaa Taresh Adday, et al.
Published: (2024-07-01)
