Drug metabolism-related gene ABCA1 augments temozolomide chemoresistance and immune infiltration abundance of M2 macrophages in glioma

Abstract Gliomas are the most prevalent primary tumor in the central nervous system, with an abysmal 5-year survival rate and alarming mortality. The current standard management of glioma is maximum resection of tumors followed by postoperative chemotherapy with temozolomide (TMZ) or radiotherapy. L...

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Bibliographic Details
Published in:	European Journal of Medical Research
Main Authors:	Yuanliang Yan, Yuanhong Liu, Qiuju Liang, Zhijie Xu
Format:	Article
Language:	English
Published:	BMC 2023-09-01
Subjects:	Glioma ABCA1 Temozolomide Chemosensitivity Drug efflux transporter
Online Access:	https://doi.org/10.1186/s40001-023-01370-6

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