Role of ICAM-1 in the Adhesion of T Cells to Enteric Glia: Perspectives in the Formation of Plexitis in Crohn’s DiseaseSummary

Background & Aims: The presence of myenteric plexitis in the proximal resection margins is a predictive factor of early postoperative recurrence in Crohn’s disease. To decipher the mechanisms leading to their formation, T-cell interactions with enteric neural cells were studied in vitro and...

Full description

Bibliographic Details
Published in:	Cellular and Molecular Gastroenterology and Hepatology
Main Authors:	Julie Pabois, Tony Durand, Catherine Le Berre, Rhiannon T. Filippone, Théo Noël, Emilie Durieu, Céline Bossard, Sarah Bruneau, Malvyne Rolli-Derkinderen, Kulmira Nurgali, Michel Neunlist, Arnaud Bourreille, Isabelle Neveu, Philippe Naveilhan
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Subjects:	Plexitis Chronic Colitis Mouse Model Lifitegrast Glial Cells
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352345X2400050X

Similar Items

Oxidative Stress-Induced HMGB1 Translocation in Myenteric Neurons Contributes to Neuropathy in Colitis
by: Rhian Stavely, et al.
Published: (2022-12-01)

Drug Repurposing for Influenza Virus Polymerase Acidic (PA) Endonuclease Inhibitor
by: Xin Meng, et al.
Published: (2021-12-01)

If SARS-CoV-2 vaccination is blamed for Parsonage–Turner syndrome, neurosurgical neurolysis is not indicated
by: Fulvio A Scorza, et al.
Published: (2024-05-01)

Lifitegrast Degradation: Products and Pathways
by: Leo Štefan, et al.
Published: (2025-10-01)

Therapeutic Potential of Combined 5% Lifitegrast and Tocopherol Eye Drops in Managing Inflammation and Oxidative Stress in Murine Dry Eye
by: Jayoung Moon, et al.
Published: (2025-01-01)

Effect of Citric Acid and Tromethamine on the Stability of Eyedrops Containing Lifitegrast
by: Ji-Su Jeong, et al.
Published: (2024-10-01)

Crosstalk between omega-6 oxylipins and the enteric nervous system: Implications for gut disorders?
by: Marine Mantel, et al.
Published: (2023-03-01)

Efficacy, safety, and tolerability of lifitegrast 5% eye drops: A randomized, double-blind, active-controlled trial in Indian patients with dry eye disease
by: Namrata Sharma, et al.
Published: (2025-01-01)

Intestinal Epithelial AMPK Deficiency Causes Delayed Colonic Epithelial Repair in DSS-Induced Colitis
by: Séverine Olivier, et al.
Published: (2022-02-01)

Managing Dry Eye Disease with Novel Medications: Mechanism, Study Validity, Safety, Efficacy, and Practical Application
by: Jason C. Wong, et al.
Published: (2024-01-01)

A Clinical Evaluation of Lifitegrast Ophthalmic Solution 5% in Symptomatic Contact Lens Wearers
by: Schulze MM, et al.
Published: (2025-08-01)

Preliminary study of cyclosporine A/Lifitegrast subconjunctival sustained-release drug membrane in the treatment of dry eyes
by: Jie Yang, et al.
Published: (2024-06-01)

teenage Pregnancy: comPlexities anD cHallenges
by: Ganesh Dangal
Published: (2006-04-01)

Orthopnea secondary to brachial plexitis with bilateral diaphragmatic paralysis
by: Mohamad El Labban, et al.
Published: (2024-01-01)

An Overview of Topical Immunomodulators used in Ophthalmology
by: Pranita Sahay, et al.
Published: (2022-01-01)

The Role of Eosinophils in Liver DiseaseSummary
by: Linxi Xie, et al.
Published: (2025-01-01)

An Improved Synthetic Process of Two Key Intermediates and Their Application in the Synthesis of Lifitegrast
by: Gang-Long Jiang, et al.
Published: (2023-09-01)

Maternal prebiotic supplementation impacts colitis development in offspring mice
by: Amélie Lê, et al.
Published: (2023-01-01)

Extensible Immunofluorescence (ExIF) accessibly generates high-plexity datasets by integrating standard 4-plex imaging data
by: Ihuan Gunawan, et al.
Published: (2025-05-01)

How leaky is the gut in Parkinson’s disease?
by: Pascal Derkinderen, et al.
Published: (2025-07-01)

Molecular Regulation and Therapeutic Targeting of VLDL Production in Cardiometabolic DiseaseSummary
by: Kendall H. Burks, et al.
Published: (2025-01-01)

Stimulation of Liver Fibrosis by N2 Neutrophils in Wilson’s DiseaseSummary
by: Xiaoxiao Mi, et al.
Published: (2023-01-01)

Visualizing enteric nervous system activity through dye-free dynamic full-field optical coherence tomography
by: Tony Durand, et al.
Published: (2023-03-01)

Unleashing the Potential of Oral Deliverable Nanomedicine in the Treatment of Inflammatory Bowel DiseaseSummary
by: Chunhua Yang, et al.
Published: (2024-01-01)

Hepatic Stellate Cells: Dictating Outcome in Nonalcoholic Fatty Liver DiseaseSummary
by: Leke Wiering, et al.
Published: (2023-01-01)

Disruption to tRNA Modification by Queuine Contributes to Inflammatory Bowel DiseaseSummary
by: Jilei Zhang, et al.
Published: (2023-01-01)

Uncovering the Relationship Between Genes and Phenotypes Beyond the Gut in Microvillus Inclusion DiseaseSummary
by: Mingyue Sun, et al.
Published: (2024-01-01)

T Cell Repertoire Homogeneity and Blood-Gut Overlap in Patients With Inflammatory Bowel DiseaseSummary
by: Kyle G. Williams, et al.
Published: (2024-01-01)

Genetic and Microbial Analysis of Invasiveness for Escherichia coli Strains Associated With Inflammatory Bowel DiseaseSummary
by: Jungyeon Kim, et al.
Published: (2025-01-01)

Enterobacteriaceae Growth Promotion by Intestinal Acylcarnitines, a Biomarker of Dysbiosis in Inflammatory Bowel DiseaseSummary
by: Johanna M.S. Lemons, et al.
Published: (2024-01-01)

Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver DiseaseSummary
by: Tianyi Chen, et al.
Published: (2023-01-01)

Neuron-to-glia and glia-to-glia signaling directs critical period experience-dependent synapse pruning
by: Nichalas Nelson, et al.
Published: (2025-02-01)

Dysfunction of ATP7B Splicing Variant Caused by Enhanced Interaction With COMMD1 in Wilson DiseaseSummary
by: Donghu Zhou, et al.
Published: (2025-01-01)

Long-term Temporal Stability of Peripheral Blood DNA Methylation Profiles in Patients With Inflammatory Bowel DiseaseSummary
by: Vincent Joustra, et al.
Published: (2023-01-01)

Co-immunostaining of ICAM-1, ICAM-2, and CD31 in Mouse Kidney Glomeruli
by: Sun-sang Sung
Published: (2020-07-01)

Fibroblast Growth Factor 19 Alters Bile Acids to Induce Dysbiosis in Mice With Alcohol-Induced Liver DiseaseSummary
by: Jessica M. Ferrell, et al.
Published: (2024-01-01)

Radial glia and radial glia-like cells: Their role in neurogenesis and regeneration
by: Yamil Miranda-Negrón, et al.
Published: (2022-11-01)

Dysregulation of cellular metabolism within the gut-brain axis is associated with behavioural changes in chronic intestinal inflammation
by: Jeannie Devereaux, et al.
Published: (2025-09-01)

Bone marrow-derived mesenchymal stem cells mitigate chronic colitis and enteric neuropathy via anti-inflammatory and anti-oxidative mechanisms
by: Rhian Stavely, et al.
Published: (2024-03-01)

Glia talk back.
by: Rachel Jones
Published: (2014-11-01)