Air pollution accelerates the development of obesity and Alzheimer’s disease: the role of leptin and inflammation - a mini-review
Air pollution is an urgent concern linked to numerous health problems in low- and middle-income countries, where 92% of air pollution-related deaths occur. Particulate matter 2.5 (PM2.5) is the most harmful component of air pollutants, increasing inflammation and changing gut microbiota, favoring ob...
| Published in: | Frontiers in Immunology |
|---|---|
| Main Authors: | Clara Machado Campolim, Bianca Camilo Schimenes, Mariana Matera Veras, Young-Bum Kim, Patricia Oliveira Prada |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-06-01
|
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2024.1401800/full |
Similar Items
Maternal exposure to air pollution alters energy balance transiently according to gender and changes gut microbiota
by: Olivia Pizetta Zordão, et al.
Published: (2023-04-01)
by: Olivia Pizetta Zordão, et al.
Published: (2023-04-01)
Leptin signaling and leptin resistance
by: Liu Jiarui, et al.
Published: (2022-08-01)
by: Liu Jiarui, et al.
Published: (2022-08-01)
Leptin and inflammatory pathways in the Alzheimer's disease continuum: Implications for glial activation and neuropsychiatric symptoms
by: Fumihiko Yasuno, et al.
Published: (2025-08-01)
by: Fumihiko Yasuno, et al.
Published: (2025-08-01)
Effects of diet-induced obesity and voluntary exercise in a tauopathy mouse model: Implications of persistent hyperleptinemia and enhanced astrocytic leptin receptor expression
by: Shunsuke Koga, et al.
Published: (2014-11-01)
by: Shunsuke Koga, et al.
Published: (2014-11-01)
Leptin, soluble leptin receptor, and free leptin index in patients with metabolic syndrome
by: Elena N. Smirnova, et al.
Published: (2017-03-01)
by: Elena N. Smirnova, et al.
Published: (2017-03-01)
PATHOGENETIC MECHANISMS OF LEPTIN RESISTANCE
by: G. A. Chumakova, et al.
Published: (2015-04-01)
by: G. A. Chumakova, et al.
Published: (2015-04-01)
Modulation of Leptin and Leptin Receptor Expression in Mice Acutely Infected with <i>Neospora caninum</i>
by: Luzia Teixeira, et al.
Published: (2020-07-01)
by: Luzia Teixeira, et al.
Published: (2020-07-01)
Leptin resistance: underlying mechanisms and diagnosis
by: Gruzdeva O, et al.
Published: (2019-01-01)
by: Gruzdeva O, et al.
Published: (2019-01-01)
Association of serum soluble leptin receptor and leptin levels with breast cancer
by: Ghorban Mohammadzadeh, et al.
Published: (2014-01-01)
by: Ghorban Mohammadzadeh, et al.
Published: (2014-01-01)
Leptin and leptin receptor expression in breast carcinomas and their relationship with clinicopathological features
by: Irem Atalay Karacay, et al.
Published: (2022-11-01)
by: Irem Atalay Karacay, et al.
Published: (2022-11-01)
Expression of leptin and leptin receptors in colorectal cancer—an immunohistochemical study
by: Saad M. Al-Shibli, et al.
Published: (2019-10-01)
by: Saad M. Al-Shibli, et al.
Published: (2019-10-01)
Stimulation of leptin secretion by insulin
by: Minglun Tsai, et al.
Published: (2012-01-01)
by: Minglun Tsai, et al.
Published: (2012-01-01)
Leptin and leptin receptor expressions in prostate tumors may predict disease aggressiveness?
by: Clarice F. Osório, et al.
Published: (2014-01-01)
by: Clarice F. Osório, et al.
Published: (2014-01-01)
Obesity and Breast Cancer: Role of Leptin
by: Flora Sánchez-Jiménez, et al.
Published: (2019-07-01)
by: Flora Sánchez-Jiménez, et al.
Published: (2019-07-01)
Estimation of Leptin and Leptin Receptor Concentrations in Seminal Plasma of Primary Infertile Men
by: Ruqaya M. AL-Barzinji, et al.
Published: (2017-07-01)
by: Ruqaya M. AL-Barzinji, et al.
Published: (2017-07-01)
Leptin and leptin receptor expression as biomarkers for breast cancer: a retrospective study
by: Yan Wang, et al.
Published: (2023-03-01)
by: Yan Wang, et al.
Published: (2023-03-01)
Assessment of expression levels of leptin and leptin receptor as potential biomarkers for risk of prostate cancer development and aggressiveness
by: Hala Fawzy Mohamed Kamel, et al.
Published: (2020-08-01)
by: Hala Fawzy Mohamed Kamel, et al.
Published: (2020-08-01)
Editorial: Leptin, obesity and diet at a glance
by: Deanne H. Hryciw, et al.
Published: (2022-11-01)
by: Deanne H. Hryciw, et al.
Published: (2022-11-01)
Leptin-Activity Modulators and Their Potential Pharmaceutical Applications
by: Marianna Greco, et al.
Published: (2021-07-01)
by: Marianna Greco, et al.
Published: (2021-07-01)
Effect of leptin concentrations and leptin receptor gene polymorphisms on the outcome of renal transplantation
by: Guadalup García-Pino, et al.
Published: (2021-04-01)
by: Guadalup García-Pino, et al.
Published: (2021-04-01)
Hypoxic Living and Exercise Training Alter Adipose Tissue Leptin/Leptin Receptor in Rats
by: Yingli Lu, et al.
Published: (2016-11-01)
by: Yingli Lu, et al.
Published: (2016-11-01)
Obesity and breast cancer: Association of serum adiponectin, leptin, and adiponectin–leptin ratio as risk biomarkers
by: Madhav Danthala, et al.
Published: (2018-01-01)
by: Madhav Danthala, et al.
Published: (2018-01-01)
Leptin and TGF-β1 Downregulate PREP1 Expression in Human Adipose-Derived Mesenchymal Stem Cells and Mature Adipocytes
by: Andreina Bruno, et al.
Published: (2021-07-01)
by: Andreina Bruno, et al.
Published: (2021-07-01)
Association of leptin and leptin receptor polymorphisms with coronary artery disease in a North Chinese Han population
by: Haidong Wang, et al.
by: Haidong Wang, et al.
The Neuronal Actions of Leptin and the Implications for Treating Alzheimer’s Disease
by: Kirsty Hamilton, et al.
Published: (2021-01-01)
by: Kirsty Hamilton, et al.
Published: (2021-01-01)
Hypothalamic TTF-1 orchestrates the sensitivity of leptin
by: Byong Seo Park, et al.
Published: (2022-12-01)
by: Byong Seo Park, et al.
Published: (2022-12-01)
Leptin in obesity and hypertension
by: Hilal Bhat, et al.
Published: (2022-03-01)
by: Hilal Bhat, et al.
Published: (2022-03-01)
Deficient leptin receptor signaling in T cells of human SLE
by: Ting Liu, et al.
Published: (2023-03-01)
by: Ting Liu, et al.
Published: (2023-03-01)
Leptin and leptin resistance in obesity: current evidence, mechanisms and future directions
by: Wenjing Hu, et al.
Published: (2025-09-01)
by: Wenjing Hu, et al.
Published: (2025-09-01)
Obesity as a Risk Factor for Alzheimer’s Disease: Implication of Leptin and Glutamate
by: Ana Lloret, et al.
Published: (2019-05-01)
by: Ana Lloret, et al.
Published: (2019-05-01)
The Effect of the Combinations of 5-Fluorouracil, Leptin and Leptin Antagonist in Glioblastoma
by: Filiz Taşpinar, et al.
Published: (2019-12-01)
by: Filiz Taşpinar, et al.
Published: (2019-12-01)
Harnessing the Power of Leptin: The Biochemical Link Connecting Obesity, Diabetes, and Cognitive Decline
by: Patricia Grasso, et al.
Published: (2022-04-01)
by: Patricia Grasso, et al.
Published: (2022-04-01)
Clinical significance of adipokine profile (leptin and adiponectin) in patients with gout
by: I.V. Orlova, et al.
Published: (2023-06-01)
by: I.V. Orlova, et al.
Published: (2023-06-01)
Advances of the Relationship between Leptin System and Non-small Cell Lung Cancer
by: Tengfei WEI, et al.
Published: (2014-04-01)
by: Tengfei WEI, et al.
Published: (2014-04-01)
Altered Brain Leptin and Leptin Receptor Expression in the 5XFAD Mouse Model of Alzheimer’s Disease
by: Anishchal A. Pratap, et al.
Published: (2020-11-01)
by: Anishchal A. Pratap, et al.
Published: (2020-11-01)
Expression analysis of leptin and leptin receptor in prostate cancer and its association with clinicopathological parameters: A case–control study
by: Piyush Gupta, et al.
Published: (2022-05-01)
by: Piyush Gupta, et al.
Published: (2022-05-01)
Subchronic exposure to 1,2-naphthoquinone induces adipose tissue inflammation and changes the energy homeostasis of mice, partially due to TNFR1 and TLR4
by: Clílton Kraüss de Oliveira Ferreira, et al.
Published: (2023-12-01)
by: Clílton Kraüss de Oliveira Ferreira, et al.
Published: (2023-12-01)
Associations Between Body Composition, Leptin, and Vitamin D Varied by the Body Fat Percentage in Adolescents
by: Rapheeporn Khwanchuea, et al.
Published: (2022-06-01)
by: Rapheeporn Khwanchuea, et al.
Published: (2022-06-01)
Sequencing of a fragment of the leptin gene in adolescents with different weight status
by: T. A. Bairova, et al.
Published: (2023-10-01)
by: T. A. Bairova, et al.
Published: (2023-10-01)
The role of leptin resistance in the development of thyroid neoplasia
by: O.S. Miroshnichenko
Published: (2023-10-01)
by: O.S. Miroshnichenko
Published: (2023-10-01)
Similar Items
-
Maternal exposure to air pollution alters energy balance transiently according to gender and changes gut microbiota
by: Olivia Pizetta Zordão, et al.
Published: (2023-04-01) -
Leptin signaling and leptin resistance
by: Liu Jiarui, et al.
Published: (2022-08-01) -
Leptin and inflammatory pathways in the Alzheimer's disease continuum: Implications for glial activation and neuropsychiatric symptoms
by: Fumihiko Yasuno, et al.
Published: (2025-08-01) -
Effects of diet-induced obesity and voluntary exercise in a tauopathy mouse model: Implications of persistent hyperleptinemia and enhanced astrocytic leptin receptor expression
by: Shunsuke Koga, et al.
Published: (2014-11-01) -
Leptin, soluble leptin receptor, and free leptin index in patients with metabolic syndrome
by: Elena N. Smirnova, et al.
Published: (2017-03-01)
