Club Cell Secretory Protein–Derived Acute Respiratory Distress Syndrome Phenotypes Predict 90-Day Mortality: A Reanalysis of the Fluids and Catheter Treatment Trial

OBJECTIVES:. Club cell secretory protein (CC16) is a protein with potential utility as a lung-specific biomarker for acute respiratory distress syndrome. The purpose of this study was to characterize CC16 in plasma from patients enrolled in the Fluid and Catheter Treatment Trial (FACTT) to determine...

Full description

Bibliographic Details
Published in:	Critical Care Explorations
Main Authors:	Aaron Chase, PharmD, Sultan Almuntashiri, PharmD, MS, Andrea Sikora, PharmD, MSCR, BCCCP, FCCM, Duo Zhang, PhD
Format:	Article
Language:	English
Published:	Wolters Kluwer 2022-06-01
Online Access:	http://journals.lww.com/10.1097/CCE.0000000000000711

Similar Items

Optimizing Pharmacist Team-Integration for ICU Patient Management: Rationale, Study Design, and Methods for a Multicentered Exploration of Pharmacist-to-Patient Ratio
by: Kelli Keats, PharmD, MPA, BCCCP, et al.
Published: (2023-09-01)

Characterizing Critical Care Pharmacy Services Across the United States
by: Robert MacLaren, PharmD, MPH, FCCM, FCCP, et al.
Published: (2021-01-01)

Practices and Outcomes Associated With Sublingual Buprenorphine Use in a Critically Ill Population
by: Denis J. Vanini, PharmD, BCCCP, et al.
Published: (2024-03-01)

A Retrospective, Single-Center Assessment of Changes in Pain, Agitation, and Delirium Management Before and During the COVID-19 Pandemic
by: Rachel L. Winner, PharmD, BCCCP, et al.
Published: (2025-01-01)

Coagulation Factor Xa (Recombinant), Inactivated-Zhzo (Andexanet Alfa) Hemostatic Outcomes and Thrombotic Event Incidence at an Academic Medical Center
by: Victoria M. Stevens PharmD, et al.
Published: (2019-12-01)

Evaluation of Hypertriglyceridemia in Critically Ill Patients With Coronavirus Disease 2019 Receiving Propofol
by: Mary P. Kovacevic, PharmD, BCCCP, BCPS, et al.
Published: (2021-01-01)

Ultrasound-Assisted Catheter-Directed Thrombolysis for the Management of Pulmonary Embolism:
by: Jasmine Ventenilla PharmD, et al.
Published: (2024-02-01)

Evaluating the impact of an emergency department protocol that guides management of methamphetamine-induced agitation and psychosis
by: Julie Nguyen, PharmD, et al.
Published: (2022-01-01)

Prevalence and Risk Factors for Iatrogenic Opioid Withdrawal in Medical Critical Care Patients
by: Marlena A. Fox, PharmD, BCPS, BCCCP, et al.
Published: (2023-05-01)

Derivation and Validation of a New Equation for Estimating Free Valproate Concentration in Critically Ill Adult Patients
by: Ji Tong Liu, PharmD, BCCCP, et al.
Published: (2023-10-01)

Precipitated withdrawal with kratom use following naltrexone administration
by: Jarka Courtney PharmD, BCPS, BCPP, et al.
Published: (2023-06-01)

Serotonin syndrome and neuroleptic malignant syndrome: A case report of intersecting symptomatology
by: Loulwa Maktabi, PharmD, BCPS, et al.
Published: (2024-02-01)

Thromboprophylaxis in Hospitalized Non-Critically Ill Patients With Mild-to-Moderate COVID-19 Infection: A Systematic Review and Meta-Analysis
by: Awatif Hafiz PharmD, BCCP, et al.
Published: (2023-08-01)

Evaluation of Latex Immunoturbidimetric Assay Thresholds and HIT in Cardiothoracic Surgery
by: Jessica Hernandez PharmD, BCCP, et al.
Published: (2023-10-01)

Evaluation of the Clinical Outcomes of Apixaban Use in Patients with Atrial Fibrillation and Uncontrolled Hypothyroidism: A Real-world Evidence
by: Khalid Al Sulaiman BCCCP, BCNSP, MBA, FCCM, et al.
Published: (2025-09-01)

The Impact of Recombinant Human Erythropoietin Administration in Critically ill COVID-19 Patients: A Multicenter Cohort Study
by: Khalid Al Sulaiman BCCCP, BCNSP, MBA, FCCM, et al.
Published: (2023-12-01)

Major Publications in the Critical Care Pharmacotherapy Literature: 2020
by: Brittany D. Bissell, PharmD, PhD, BCCCP, et al.
Published: (2021-12-01)

Clinical outcomes for patients on antiplatelet and anticoagulants in thoracoabdominal trauma
by: Victoria Sharp, DO, FACS, FACOS, et al.
Published: (2023-12-01)

Evaluation of Hydrocortisone Discontinuation Strategies in Septic Shock: A Retrospective Cohort Study
by: Hanine O. AlMubayedh, PharmD, BCPS, BCCCP, et al.
Published: (2025-07-01)

Ketamine for Primary Analgosedation in Critically Ill Surgery and Trauma Patients Requiring Mechanical Ventilation
by: Bradley J. Peters, PharmD, BCPS, BCCCP, et al.
Published: (2024-02-01)

A Review and Clinical Understanding of Tenofovir: Tenofovir Disoproxil Fumarate versus Tenofovir Alafenamide
by: Chanie Wassner PharmD, BCCCP, BCIDP, et al.
Published: (2020-04-01)

PHarmacist Avoidance or Reductions in Medical Costs in CRITically Ill Adults: PHARM-CRIT Study
by: Megan A. Rech, PharmD, MS, FCCM, et al.
Published: (2021-12-01)

Doxycycline’s Potential Role in Reducing Thrombosis and Mortality in Critically Ill Patients With COVID-19: A Multicenter Cohort Study
by: Khalid Al Sulaiman MBA, BCCCP, BCNSP, FCCM, et al.
Published: (2023-06-01)

Formulary Reconciliation: Implementation of a Comprehensive Approach to Formulary Maintenance and Standardization
by: Janine G. Martino PharmD, BCOP, APh, et al.
Published: (2024-08-01)

Knowledge, Attitude and Practice Related to Chemotherapy Among Cancer Patients
by: Muzna Suhail MPhil, et al.
Published: (2024-04-01)

Characterization of hospitalized patients who received naloxone while receiving opioids with or without gabapentinoids
by: Payal H. Desai, PharmD, BCCCP, et al.
Published: (2021-07-01)

Alternatives to Hydrocortisone for Hemodynamic Support in Septic Shock Management Due to Medication Shortage
by: Mohammed Aldhaeefi, PharmD, et al.
Published: (2023-07-01)

A Systematic Review and Meta-Analysis Evaluating Geographical Variation in Outcomes of Cancer Patients Treated in ICUs
by: Lama H. Nazer, PharmD, FCCM, et al.
Published: (2022-09-01)

Evaluation of the Safety and Effectiveness of Topical Intrapleural Application of Tranexamic Acid in Thoracic Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
by: Amer Alzahrani MD RRT, et al.
Published: (2023-12-01)

Optimal Dosage and Administration Practices for Vitamin K Antagonist Reversal With 4-Factor Prothrombin Complex Concentrate
by: Denise H. Rhoney PharmD, FCCP, FCCM, FNCS, et al.
Published: (2020-10-01)

Evaluation of the tacrolimus drug interaction with voriconazole vs clotrimazole in heart transplant recipients
by: Elizabeth Posney, PharmD, et al.
Published: (2024-05-01)

Impact of traditional versus nontraditional initiation dosing schedule of paliperidone palmitate on 30-day readmission and safety
by: Erika Kim, PharmD, BCPP, et al.
Published: (2023-12-01)

Adverse childhood experiences among California student pharmacists
by: Shawn R. Smith, PharmD, APh, et al.
Published: (2024-02-01)

Major Publications in the Critical Care Pharmacotherapy Literature: 2022
by: Payal K. Gurnani, PharmD, FCCM, et al.
Published: (2023-10-01)

Outcomes Associated with Time in Therapeutic Range for Patients Receiving Intravenous Unfractionated Heparin
by: Mujtaba Mahmud PharmD, et al.
Published: (2025-08-01)

Assessing intradisciplinary pharmacy communication related to transitions of care
by: Letitia N. Warunek, PharmD, BCPS, et al.
Published: (2024-06-01)

A retrospective review of intramuscular olanzapine and parenteral benzodiazepine coadministration in the emergency department
by: Jessica Laub, PharmD, BCEMP, et al.
Published: (2024-08-01)

Pharmacologic management of adolescent catatonia: A dual-case series
by: Lauren Leiby, PharmD, BCPP, et al.
Published: (2024-06-01)

Efficacy of Berberine Alone and in Combination for the Treatment of Hyperlipidemia: A Systematic Review
by: Laura M. Koppen PharmD, et al.
Published: (2017-10-01)

Community Pharmacy-Based Blood Pressure Screening in Newfoundland and Labrador, Canada for World Hypertension Day 2022: A Cross-Sectional Study
by: Tiffany A. Lee, BSc(Pharm), PharmD, PhD(c), et al.
Published: (2024-05-01)