Asthma in elite athletes – do they have Type 2 or non-Type 2 disease? A new insight on the endotypes among elite athletes

Asthma and exercise-induced bronchoconstriction are highly prevalent in elite athletes compared with the general population. Some athletes have classic asthma with allergic sensitization; however, it seems that a proportion of athletes develop asthma as a result of several years of intensive trainin...

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Bibliographic Details
Published in:Frontiers in Allergy
Main Authors: Søren Malte Rasmussen, Erik Sören Halvard Hansen, Vibeke Backer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
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Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2022.973004/full
Description
Summary:Asthma and exercise-induced bronchoconstriction are highly prevalent in elite athletes compared with the general population. Some athletes have classic asthma with allergic sensitization; however, it seems that a proportion of athletes develop asthma as a result of several years of intensive training. It leads us to believe that asthma in athletes consists of at least two distinct endotypes – classic early-onset, Type 2 mediated asthma, and asthma with later onset caused by exercise which might be classified as non-Type 2 asthma. The purpose of this review is to evaluate the current literature on asthma in athletes focusing on inflammation and examine if asthma in athletes could be characterized as either Type 2- or non-Type 2 asthma.
ISSN:2673-6101