Evaluation of bacteriophage cocktail on urinary tract infection caused by colistin-resistant Klebsiella pneumoniae in mice model

Objective: The colistin-resistant Klebsiella pneumoniae causes complicated urinary tract infections (UTIs). Of them, 73% of strains of K. pneumoniae formed moderate to strong biofilm. Multidrug-resistant (MDR)/Pandrug-resistant (PDR) bacteria causing UTIs are very challenging to conventional antibio...

Full description

Bibliographic Details
Published in:	Journal of Global Antimicrobial Resistance
Main Authors:	Alakh Narayan Singh, Aprajita Singh, Gopal Nath
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Subjects:	Klebsiella pneumoniae UTI Bacteriophage MDR PDR
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213716524001504

Similar Items

Isolation and characterization of two novel bacteriophages against carbapenem-resistant Klebsiella pneumoniae
by: Abrar Senhaji-Kacha, et al.
Published: (2024-08-01)

Isolation and Identification of Multidrug-Resistant <i>Klebsiella pneumoniae</i> Clones from the Hospital Environment
by: María Guadalupe Córdova-Espinoza, et al.
Published: (2023-04-01)

Designing phage cocktails to combat the emergence of bacteriophage-resistant mutants in multidrug-resistant Klebsiella pneumoniae
by: Seongjun Yoo, et al.
Published: (2024-01-01)

Urinary Tract Infections Caused by K. pneumoniae in Kidney Transplant Recipients – Epidemiology, Virulence and Antibiotic Resistance
by: Beata Krawczyk, et al.
Published: (2022-04-01)

In vitro efficacy of bacteriophage and colistin combinations in eradicating biofilm formed by colistin-resistant Enterobacter cloacae complex
by: Srishti Singh, et al.
Published: (2025-09-01)

How Phages Overcome the Challenges of Drug Resistant Bacteria in Clinical Infections
by: Taati Moghadam M, et al.
Published: (2020-01-01)

The Role of Antibiotic Resistant <i>A. baumannii</i> in the Pathogenesis of Urinary Tract Infection and the Potential of Its Treatment with the Use of Bacteriophage Therapy
by: Natalia Bagińska, et al.
Published: (2021-03-01)

Potential of an Isolated Bacteriophage to Inactivate <i>Klebsiella pneumoniae</i>: Preliminary Studies to Control Urinary Tract Infections
by: João Duarte, et al.
Published: (2024-02-01)

Detection of Quinolone Resistance Genes of Klebsiella pneumoniae Isolated from Patients with Urinary Tract Infection attending Some Selected Hospitals in Irbid, Jordan
by: Idris, S.L., et al.
Published: (2017-12-01)

The potential use of bacteriophages as antibacterial agents against Klebsiella pneumoniae
by: Omid Gholizadeh, et al.
Published: (2024-08-01)

Enterococcus-associated urinary tract infections, their prevalence and antibiotic resistance
by: Obe OA, et al.
Published: (2024-09-01)

Topically Applied Bacteriophage to Control Multi-Drug Resistant <i>Klebsiella pneumoniae</i> Infected Wound in a Rat Model
by: Mohamed S. Fayez, et al.
Published: (2021-08-01)

High activity and specificity of bacteriophage cocktails against carbapenem-resistant Klebsiella pneumoniae belonging to the high-risk clones CG258 and ST307
by: Sara Tellez-Carrasquilla, et al.
Published: (2024-12-01)

In vitro effect of fosfomycin on multi-drug resistant gram-negative bacteria causing urinary tract infections
by: Gopichand P, et al.
Published: (2019-07-01)

Fosfomycin, interesting alternative drug for treatment of urinary tract infections created by multiple drug resistant and extended spectrum β-lactamase producing strains
by: Fatemeh Yeganeh-Sefidan, et al.
Published: (2016-05-01)

Therapeutic Potential of an Azithromycin-Colistin Combination against XDR <i>K. pneumoniae</i> in a 3D Collagen-Based In Vitro Wound Model of a Biofilm Infection
by: Olena V. Moshynets, et al.
Published: (2023-02-01)

Morphological, biological, and genomic characterization of Klebsiella pneumoniae phage vB_Kpn_ZC2
by: Mohamed S. Fayez, et al.
Published: (2023-05-01)

Isolation and Characterization of a Klebsiella pneumoniae Specific Lytic Bacteriophage from a Hospital Waste-water Treatment Plant
by: Mahboubeh Soleimani Sasani, et al.
Published: (2019-01-01)

In Vitro and In Vivo Assessments of Two Newly Isolated Bacteriophages against an ST13 Urinary Tract Infection <i>Klebsiella pneumoniae</i>
by: Fanny Laforêt, et al.
Published: (2022-05-01)

Identification and preclinical efficacy evaluation of two lytic bacteriophages targeting highly virulent and multidrug-resistant Klebsiella pneumoniae
by: Ai Guo, et al.
Published: (2025-08-01)

Isolation and Characterization of Effective Lytic Bacteriophages to Control the Antibiotic Resistant Klebsiella Pneumoniae Infections in Noth-West of Iran
by: Raheleh Majdani, et al.
Published: (2024-04-01)

Isolation and Identification of Multi-Drug Resistant (MDR) Pathogens from Patients with Urinary Tract Infection (UTI) in Dhaka City, Bangladesh
by: Fatema Khatun, et al.
Published: (2022-09-01)

Genomic analysis and therapeutic efficacy evaluation of bacteriophage PK2420 for pneumonia caused by hypervirulent Klebsiella pneumoniae (K20 serotype)
by: Jinfeng Chen, et al.
Published: (2025-05-01)

Treatment of Acinetobacter baumannii by Specialized ϕTZ Bacteriophage and Studying of pH Effect on Bacteriophage Stability and Efficacy
by: Taha Yaseen Ibrahim
Published: (2022-12-01)

Isolation and characterization of lytic bacteriophage from waste water to control clinical multidrug resistant Klebsiella pneumoniae
by: Muhammad R.A. Shah, et al.
Published: (2023-10-01)

Ackermannviridae bacteriophage against carbapenem-resistant Klebsiella pneumoniae of capsular type 64
by: Juan Li, et al.
Published: (2024-09-01)

Extended spectrum beta-lactamase production and blaCTX-M gene in Escherichia coli and Klebsiella pneumoniae causing urinary tract infection at a tertiary care hospital in Nepal
by: Gaurab Pandey, et al.
Published: (2024-04-01)

“Sichuanvirus”, a novel bacteriophage viral genus, able to lyse carbapenem-resistant Klebsiella pneumoniae
by: Juan Li, et al.
Published: (2025-01-01)

Carbapenem-Resistant <i>Enterobacteriaceae</i> in Urinary Tract Infections: From Biological Insights to Emerging Therapeutic Alternatives
by: Eugenio Bologna, et al.
Published: (2024-01-01)

Colistin resistance in Escherichia coli and Klebsiella pneumoniae in humans and backyard animals in Ecuador
by: Carlos Bastidas-Caldes, et al.
Published: (2023-04-01)

Microbial Detection and Antibiotic Susceptibility patterns of Clinical Isolates from Women With Urinary Tract Infection in AL-Nasiriyah City/Iraq
by: Muna Jihad, et al.
Published: (2024-06-01)

Novel Bacteriophage Cocktail, Endolysin-Hydroxyethyl Cellulose Gel, and Mixture Gel Therapy for Acne Vulgaris Caused by Multidrug Resistant Propionibacterium (Cutibacterium) acnes
by: Haneen Emad Hussain, et al.
Published: (2025-07-01)

Characterizing the bacteriophage PKp-V1 as a potential treatment for ESBL-producing hypervirulent K1 Klebsiella pneumoniae ST258 isolated from veterinary specimens
by: Muhammad Usama Tariq, et al.
Published: (2024-09-01)

Predictive modeling of multidrug resistance in female genital infections: implications for early urinary tract infection detection
by: Francis Chukwuebuka Ihenetu, et al.
Published: (2025-06-01)

Evaluation of the therapeutic effect of a novel bacteriophage in the healing process of infected wounds with Klebsiella pneumoniae in mice
by: Fatemeh Zeynali Kelishomi, et al.
Published: (2024-03-01)

In Vitro Activity, Stability and Molecular Characterization of Eight Potent Bacteriophages Infecting Carbapenem-Resistant <i>Klebsiella pneumoniae</i>
by: Abeer Ameen Baqer, et al.
Published: (2022-12-01)

Phenotypic characterization of ESBL-producing urinary isolates of E. coli and Klebsiella spp. in a tertiary care children's hospital in Nepal
by: Santosh Pantha, et al.
Published: (2024-03-01)

Characterization of two lytic bacteriophages infecting carbapenem-resistant clinical Klebsiella pneumoniae in Dhaka, Bangladesh
by: Nishat Tasnim Ananna, et al.
Published: (2024-12-01)

Isolation and characterization of lytic bacteriophage vB_KpnP_23: A promising antimicrobial candidate against carbapenem-resistant Klebsiella pneumoniae
by: Qian Wang, et al.
Published: (2024-12-01)

Salphage: salvage bacteriophage therapy for a recalcitrant Klebsiella pneumoniae prosthetic shoulder infection — a case report
by: James B Doub, et al.
Published: (2022-09-01)