Leptin Induces Mitosis and Activates the Canonical Wnt/β-Catenin Signaling Pathway in Neurogenic Regions of Xenopus Tadpole Brain

In addition to its well-known role as an adipostat in adult mammals, leptin has diverse physiological and developmental actions in vertebrates. Leptin has been shown to promote development of hypothalamic circuits and to induce mitosis in different brain areas of mammals. We investigated the ontogen...

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Bibliographic Details
Published in:	Frontiers in Endocrinology
Main Authors:	Melissa Cui Bender, Christopher J. Sifuentes, Robert J. Denver
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-05-01
Subjects:	leptin neurogenesis Xenopus metamorphosis Wnt/β-catenin
Online Access:	http://journal.frontiersin.org/article/10.3389/fendo.2017.00099/full

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