Inmunopatogenia de la psoriasis. Impacto en las manifestaciones clínicas y el tratamiento de la enfermedad Immunopathogenesis of psoriasis. Impact on clinical manifestations and its treatment

La psoriasis es una enfermedad inflamatoria crónica de la piel mediada por células T que afecta a individuos con predisposición genética y presenta varios subtipos clínicos. Se caracteriza por la presencia de placas eritematosas bien definidas, escamosas y de bordes irregulares, que afectan fundamen...

Full description

Bibliographic Details
Published in:	Revista Cubana de Hematología, Inmunología y Hemoterapia
Main Author:	María Elena Alfonso-Valdés
Format:	Article
Language:	Spanish
Published:	Editorial Ciencias Médicas 2012-12-01
Subjects:	psoriasis inmunopatogenia células T IFNa células dendríticas plasmacitoides células Th17 eje IL-23/Th17 immunopathogenesis T cells plasmacytoid dendritic cells Th17 cells IL-23/Th17 axis
Online Access:	http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-02892012000400005

Similar Items

HMGB1 regulates Th17 cell differentiation and function in patients with psoriasis
by: Xiaofeng Zhu, et al.
Published: (2024-02-01)

Dihydroartemisinin Alleviates Imiquimod-Induced Psoriasis-like Skin Lesion in Mice Involving Modulation of IL-23/Th17 Axis
by: Jiang-Min Liu, et al.
Published: (2021-08-01)

Heparanase contributes to psoriatic lesions through crosstalk with IL-17 pathway
by: Chengyao Zhu, et al.
Published: (2023-01-01)

IL-21 Induces an Imbalance of Th17/Treg Cells in Moderate-to-Severe Plaque Psoriasis Patients
by: Yuling Shi, et al.
Published: (2019-08-01)

The inflammatory cytokine interleukin-23 is elevated in lung cancer, particularly small cell type
by: Caner Cam, et al.
Published: (2016-08-01)

Bidirectional Association between Psoriasis and Asthma: A Systematic Review and Meta-Analysis
by: Ashley Garcia, et al.
Published: (2023-05-01)

Revisiting the interleukin 17 family of cytokines in psoriasis: pathogenesis and potential targets for innovative therapies
by: Nicolo Costantino Brembilla, et al.
Published: (2023-05-01)

Traditional Chinese Medicine Shi-Bi-Man ameliorates psoriasis via inhibiting IL-23/Th17 axis and CXCL16-mediated endothelial activation
by: Chenyang Zhang, et al.
Published: (2024-03-01)

Psoriasis and Leprosy: An Arcane Relationship
by: Ge G, et al.
Published: (2023-06-01)

p19-targeted ABD-derived protein variants inhibit IL-23 binding and exert suppressive control over IL-23-stimulated expansion of primary human IL-17+ T-cells
by: Lucie Křížová, et al.
Published: (2017-02-01)

Corrigendum: The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases
by: Victoria Navarro-Compán, et al.
Published: (2023-11-01)

The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases
by: Victoria Navarro-Compán, et al.
Published: (2023-08-01)

Alopecia Diffusa while Using Interleukin-17 Inhibitors against Psoriasis Vulgaris
by: Makiko Yajima, et al.
Published: (2019-03-01)

The Impact of Treatment with IL-17/IL-23 Inhibitors on Subclinical Atherosclerosis in Patients with Plaque Psoriasis and/or Psoriatic Arthritis: A Systematic Review
by: Aikaterini Tsiogka, et al.
Published: (2023-01-01)

IL-15 negatively regulates curdlan-induced IL-23 production by human monocyte-derived dendritic cells and subsequent Th17 response
by: Ahmet Eken, et al.
Published: (2019-11-01)

Th17-Inducing Cytokines IL-6 and IL-23 Are Crucial for Granuloma Formation during Experimental Paracoccidioidomycosis
by: Fabrine Sales Massafera Tristão, et al.
Published: (2017-08-01)

Weight loss improves inflammation by T helper 17 cells in an obese patient with psoriasis at high risk for cardiovascular events
by: Yoshiro Maezawa, et al.
Published: (2023-09-01)

Autoimmune diseases in the TH17 era
by: D. Mesquita Jr., et al.
Published: (2009-06-01)

RETRACTED ARTICLE: Identification of novel IL17-related genes as prognostic and therapeutic biomarkers of psoriasis using comprehensive bioinformatics analysis and machine learning
by: Xingling He, et al.
Published: (2025-04-01)

Inheritance-Specific Dysregulation of Th1- and Th17-Associated Cytokines in Alopecia Areata
by: Monica M. Van Acker, et al.
Published: (2023-08-01)

Bimekizumab for the Treatment of Psoriasis: A Review of the Current Knowledge
by: Ruggiero A, et al.
Published: (2022-06-01)

Characteristics and sources of tissue-resident memory T cells in psoriasis relapse
by: Canbin Dong, et al.
Published: (2023-01-01)

Th17 Cells in Viral Infections—Friend or Foe?
by: Iury Amancio Paiva, et al.
Published: (2021-05-01)

Evaluation of the Th17 pathway in psoriasis and geographic tongue,
by: Bruna Lavinas Sayed Picciani, et al.
Published: (2020-02-01)

Study on the therapeutic effects of Qinghuang ointment in a mouse model of imiquimod-induced psoriasis and its underlying mechanisms
by: LIU Dan, et al.
Published: (2025-05-01)

Hidradenitis suppurativa and psoriasis: the odd couple
by: Laura Macca, et al.
Published: (2023-07-01)

Interleukin-17A Drives IL-19 and IL-24 Expression in Skin Stromal Cells Regulating Keratinocyte Proliferation
by: Xiaofei Xu, et al.
Published: (2021-09-01)

Activated IL-23/IL-17 pathway closely correlates with increased Foxp3 expression in livers of chronic hepatitis B patients
by: Mao Qing, et al.
Published: (2011-04-01)

Positive and Negative Regulation of Th17 Cell Differentiation: Evaluating The Impact of RORC2
by: Mazdak Ganjalikhani Hakemi, et al.
Published: (2014-04-01)

Safety of interleukin inhibitors in patients with plaque psoriasis and history of neoplasms: a multicenter retrospective study – IL PSO (Italian landscape psoriasis)
by: Mario Valenti, et al.
Published: (2025-12-01)

Expression of il-23/th17 pathway in a murine model of coxsackie virus b3-induced viral myocarditis
by: Kong Qing, et al.
Published: (2011-06-01)

Role of interleukin 17 (IL-17) in the inflammatory hypothesis of depression
by: Katarzyna Bliźniewska-Kowalska, et al.
Published: (2023-12-01)

Interleukin-17 Links Inflammatory Cross-Talks Between Comorbid Psoriasis and Atherosclerosis
by: Yan Wang, et al.
Published: (2022-04-01)

Expression of Helper and Regulatory T Cells in Atopic Dermatitis: A Meta-Analysis
by: Dao-jun Zhang, et al.
Published: (2022-04-01)

AIEC-dependent pathogenic Th17 cell transdifferentiation in Crohn’s disease is suppressed by rfaP and ybaT deletion
by: G. Leccese, et al.
Published: (2024-12-01)

Therapeutic Advances in Psoriasis: From Biologics to Emerging Oral Small Molecules
by: Francesco Ferrara, et al.
Published: (2024-09-01)

An increased expression profile of Th9/IL-9 correlated with Th17/IL-17 in patients with immune thrombocytopenia
by: Jianlin Qiao, et al.
Published: (2017-04-01)

IL-1β but not programmed death-1 and programmed death-ligand pathway is critical for the human Th17 response to M. tuberculosis
by: Emmanuel Stephen-Victor, et al.
Published: (2016-11-01)

Th17/1 and ex-Th17 cells are detected in patients with polyarticular juvenile arthritis and increase following treatment
by: Stephanie Wood, et al.
Published: (2024-03-01)

The regulatory mechanism and potential application of IL-23 in autoimmune diseases
by: De-Kai Xiong, et al.
Published: (2022-09-01)