Case study: Targeted RNA-sequencing of aged formalin-fixed paraffin-embedded samples for understanding chemical mode of action

Formalin-fixed paraffin-embedded (FFPE) samples are the only remaining biological archive for many toxicological and clinical studies, yet their use in genomics has been limited due to nucleic acid damage from formalin fixation. Older FFPE samples with highly degraded RNA pose a particularly difficu...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Toxicology Reports
المؤلفون الرئيسيون:	Michael D. Cannizzo, Charles E. Wood, Susan D. Hester, Leah C. Wehmas
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2022-01-01
الموضوعات:	Formalin-fixed paraffin-embedded (FFPE) RNA-Seq TempO-Seq Dichloroacetic acid DCA Benchmark dose (BMD) analysis
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2214750022000956

مواد مشابهة

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