Aminoclay Nanoparticles Induce Anti-Inflammatory Dendritic Cells to Attenuate LPS-Elicited Pro-Inflammatory Immune Responses

Although 3-aminopropyl functionalized magnesium phyllosilicate nanoparticles (hereafter aminoclay nanoparticles, ACNs) are well-known nanomaterials employed as drug carriers, their effects on immune cells remain unclear. To address this issue, we explored murine dendritic cells (DCs) as these cells...

Full description

Bibliographic Details
Published in:	Molecules
Main Authors:	Hyun Jung Park, Sung Won Lee, Jae Geun Song, Luc Van Kaer, Jae Hee Cheon, Soo-Jeong Lim, Hyo-Kyung Han, Seokmann Hong
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Subjects:	aminoclay dendritic cells lipopolysaccharide (LPS) IL1β
Online Access:	https://www.mdpi.com/1420-3049/27/24/8743

Similar Items

Highly promoted CO2 separation of poly(ether-block-amide) based mixed matrix membranes using MOFs@aminoclay architectures as fillers
by: Zohreh Tajdini, et al.
Published: (2024-11-01)

Loading Effects of Aminoclays in Co-Culture of Two Cyanobacterial <i>Microcystis</i> and <i>Anabaena</i> Species as an Algicidal Role
by: Minh Kim Nguyen, et al.
Published: (2021-06-01)

Gelsolin Inhibits the Inflammatory Process Induced by LPS
by: Ying Cheng, et al.
Published: (2017-01-01)

UV-Light-Driven Enhancement of Peroxidase-Like Activity of Mg-Aminoclay-Based Fe<sub>3</sub>O<sub>4</sub>/TiO<sub>2</sub> Hybrids for Colorimetric Detection of Phenolic Compounds
by: Yoon Jung Jang, et al.
Published: (2021-08-01)

Lipid/Clay-Based Solid Dispersion Formulation for Improving the Oral Bioavailability of Curcumin
by: Jae Geun Song, et al.
Published: (2022-10-01)

Enhanced oral delivery of insulin via the colon-targeted nanocomposite system of organoclay/glycol chitosan/Eudragit®S100
by: Sang Hoon Lee, et al.
Published: (2020-07-01)

Lnc-MALAT1 attenuates miR-217 inhibiting LPS-induced inflammatory response in rat alveolar macrophages
by: LUO Chuan-ling, SUN Li-ping, QI Cheng-dong
Published: (2021-03-01)

Reproducibility of LPS-Induced ex vivo Cytokine Response of Healthy Volunteers Using a Whole Blood Assay
by: Jorda A, et al.
Published: (2024-07-01)

Resveratrol pretreatment mitigates LPS-induced acute lung injury by regulating conventional dendritic cells’ maturation and function
by: Guo Bingnan, et al.
Published: (2021-09-01)

Skeletal Muscle Myofibers Directly Contribute to LPS-Induced Systemic Inflammatory Tone
by: Joseph J. Bivona III, et al.
Published: (2022-06-01)

The multi-faceted role of NADPH in regulating inflammation in activated myeloid cells
by: Kenneth K. Y. Ting, et al.
Published: (2023-12-01)

Increased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand
by: Galy Anne, et al.
Published: (2002-10-01)

Protective Effect of Resveratrol Improves Systemic Inflammation Responses in LPS-Injected Lambs
by: Yanping Liang, et al.
Published: (2019-10-01)

Estimation of Resilience Parameters Following LPS Injection Based on Activity Measured With Computer Vision
by: Lisette E. van der Zande, et al.
Published: (2022-07-01)

The protective effects of saxagliptin against lipopolysaccharide (LPS)-induced inflammation and damage in human dental pulp cells
by: Xinxing Guo, et al.
Published: (2019-12-01)

Investigation of the Effects of Fingolimod on the LPS-Induced Inflammatory Response in the HUVEC Cell Line
by: Hamza Halıcı, et al.
Published: (2025-07-01)

Kinetic Changes in B7 Costimulatory Molecules and IRF4 Expression in Human Dendritic Cells during LPS Exposure
by: Henry Velazquez-Soto, et al.
Published: (2022-07-01)

Puerarin attenuates LPS-induced renal inflammatory response of mice
by: FENG Na, TANG Jie, HE Xi-ju, TIAN Zong-ying, SHI Dan-dan, YU Jing-jing
Published: (2022-11-01)

Scutellarein Suppresses the Production of ROS and Inflammatory Mediators of LPS-Activated Bronchial Epithelial Cells and Attenuates Acute Lung Injury in Mice
by: Ximeng Li, et al.
Published: (2024-06-01)

Organometallic Phyllosilicate-Gold Nanocomplex: An Effective Oral Delivery System of Methotrexate for Enhanced in vivo Efficacy Against Colorectal Cancer
by: Bajracharya R, et al.
Published: (2023-12-01)

LPS promotes the production of ROS in neutrophils to regulate their killing activity against Mycobacterium tuberculosis
by: Lina Jiang, et al.
Published: (2025-07-01)

The Contact Allergen NiSO4 Triggers a Distinct Molecular Response in Primary Human Dendritic Cells Compared to Bacterial LPS
by: Tessa Höper, et al.
Published: (2021-03-01)

Carvacrol alleviates LPS-induced myocardial dysfunction by inhibiting the TLR4/MyD88/NF-κB and NLRP3 inflammasome in cardiomyocytes
by: Lu Xu, et al.
Published: (2024-11-01)

Effect of Aster tataricus on production of inflammatory mediators in LPS stimulated rat astrocytoma cell line (C6) and THP-1 cells
by: Hong-tao Zhang, et al.
Published: (2017-03-01)

Molecular Mechanisms of the Anti-Inflammatory Effects of Epigallocatechin 3-Gallate (EGCG) in LPS-Activated BV-2 Microglia Cells
by: Ashley Payne, et al.
Published: (2023-04-01)

Dexamethasone has profound influence on the energy metabolism of porcine blood leukocytes and prevents the LPS-induced glycolytic switch
by: Wenjuan Ma, et al.
Published: (2025-02-01)

Metformin Protective Effects in LPS-Induced Alzheimer's Disease Mice Model: NO-cGMP-KATP Pathway Involvement
by: Mojtaba Dolatshahi, et al.
Published: (2025-05-01)

The regenerating gene (Reg) family genes in inflammatory bowel disease (IBD)
by: Shin Takasawa, et al.
Published: (2025-02-01)

Pinosylvin Shifts Macrophage Polarization to Support Resolution of Inflammation
by: Konsta Kivimäki, et al.
Published: (2021-05-01)

Modulation of the main porcine enteric neuropeptides by a single low-dose of lipopolysaccharide (LPS) Salmonella Enteritidis
by: Anita Mikołajczyk, et al.
Published: (2017-12-01)

Aquaporin-9 Contributes to the Maturation Process and Inflammatory Cytokine Secretion of Murine Dendritic Cells
by: Stefania De Santis, et al.
Published: (2018-10-01)

Bacterial Metabolite Reuterin Attenuated LPS-Induced Oxidative Stress and Inflammation Response in HD11 Macrophages
by: Yibin Xu, et al.
Published: (2022-08-01)

Astaxanthin Provides Antioxidant Protection in LPS-Induced Dendritic Cells for Inflammatory Control
by: Yinyan Yin, et al.
Published: (2021-09-01)

UFL1 Alleviates LPS-Induced Apoptosis by Regulating the NF-κB Signaling Pathway in Bovine Ovarian Granulosa Cells
by: Xinling Wang, et al.
Published: (2020-02-01)

Vaccinium bracteatum extract alleviates inflammatory responses in LPS-stimulated RAW264.7 macrophages
by: Weerawan Rod-in, et al.
Published: (2025-03-01)

Physcion Mitigates LPS-Induced Neuroinflammation, Oxidative Stress, and Memory Impairments via TLR-4/NF-кB Signaling in Adult Mice
by: Sareer Ahmad, et al.
Published: (2024-09-01)

Fabrication and Evaluation of a pH-Responsive Nanocomposite-Based Colonic Delivery System for Improving the Oral Efficacy of Liraglutide
by: Song JG, et al.
Published: (2023-07-01)

Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction
by: Yinyan Yin, et al.
Published: (2021-06-01)

In-depth biological characterization of two black soldier fly anti-Pseudomonas peptides reveals LPS-binding and immunomodulating effects
by: Laurence Van Moll, et al.
Published: (2023-10-01)

The Battle of LPS Clearance in Host Defense vs. Inflammatory Signaling
by: Pankaj Kumar, et al.
Published: (2024-09-01)