Presence of V72I, G123S and R127K Integrase Inhibitor polymorphisms could reduce ART effectiveness: a retrospective longitudinal study
Objectives: Structural aspects of HIV-1 integrase complex and role of integrase minor mutations and polymorphisms in ART effectiveness is still unknown. The objective of this study was to assess the 24 and 48 weeks (W) effectiveness of ART regimens in patients with Integrase Inhibitors (InSTI) minor...
| 出版年: | HIV Research & Clinical Practice |
|---|---|
| 主要な著者: | Anna Celotti, Franco Gargiulo, Eugenia Quiros-Roldan, Martina Properzi, Maria Antonia De Francesco, Davide Coletto, Francesca Caccuri, Ilaria Izzo, Arnaldo Caruso, Francesco Castelli, Emanuele Focà |
| フォーマット: | 論文 |
| 言語: | 英語 |
| 出版事項: |
Taylor & Francis Group
2020-01-01
|
| 主題: | |
| オンライン・アクセス: | http://dx.doi.org/10.1080/25787489.2020.1734753 |
類似資料
First Reported Case of Integrase Strand Transfer Inhibitor Resistance in Suriname: Unusual Drug Resistance Mutations Following Exposure to Dolutegravir
著者:: Rachel C. Sno, 等
出版事項: (2025-02-01)
著者:: Rachel C. Sno, 等
出版事項: (2025-02-01)
Genetic Features of HIV-1 Integrase Sub-Subtype A6 Predominant in Russia and Predicted Susceptibility to INSTIs
著者:: Alina Kirichenko, 等
出版事項: (2020-07-01)
著者:: Alina Kirichenko, 等
出版事項: (2020-07-01)
A clinical review of HIV integrase strand transfer inhibitors (INSTIs) for the prevention and treatment of HIV-1 infection
著者:: Alexa Vyain Zhao, 等
出版事項: (2022-10-01)
著者:: Alexa Vyain Zhao, 等
出版事項: (2022-10-01)
Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs
著者:: Steven J. Smith, 等
出版事項: (2021-01-01)
著者:: Steven J. Smith, 等
出版事項: (2021-01-01)
Changes in central adipose tissue after switching to integrase inhibitors
著者:: Paula Debroy, 等
出版事項: (2020-11-01)
著者:: Paula Debroy, 等
出版事項: (2020-11-01)
Efficacy of Integrase Strand Transfer Inhibitors and the Capsid Inhibitor Lenacapavir against HIV-2, and Exploring the Effect of Raltegravir on the Activity of SARS-CoV-2
著者:: Irene Wanjiru Kiarie, 等
出版事項: (2024-10-01)
著者:: Irene Wanjiru Kiarie, 等
出版事項: (2024-10-01)
Cell Culture Evaluation Hints Widely Available HIV Drugs Are Primed for Success if Repurposed for HTLV-1 Prevention
著者:: Mphatso D. Kalemera, 等
出版事項: (2024-06-01)
著者:: Mphatso D. Kalemera, 等
出版事項: (2024-06-01)
Pre-Treatment Integrase Inhibitor Resistance and Natural Polymorphisms among HIV-1 Subtype C Infected Patients in Ethiopia
著者:: Dawit Assefa Arimide, 等
出版事項: (2022-03-01)
著者:: Dawit Assefa Arimide, 等
出版事項: (2022-03-01)
META-INSTI: metabolic adverse events following integrase strand transfer inhibitor administration in spontaneous adverse event reports
著者:: Milena M Murray, 等
出版事項: (2023-08-01)
著者:: Milena M Murray, 等
出版事項: (2023-08-01)
Development and Optimization of Oligonucleotide Ligation Assay (OLA) Probes for Detection of HIV-1 Resistance to Dolutegravir
著者:: Ingrid A. Beck, 等
出版事項: (2024-07-01)
著者:: Ingrid A. Beck, 等
出版事項: (2024-07-01)
HIV-1 diversity and pre-treatment drug resistance in the era of integrase inhibitor among newly diagnosed ART-naïve adult patients in Luanda, Angola
著者:: Cruz S. Sebastião, 等
出版事項: (2024-07-01)
著者:: Cruz S. Sebastião, 等
出版事項: (2024-07-01)
Lack of activity of HIV-1 integrase strand-transfer inhibitors on recombinase activating gene (RAG) activity at clinically relevant concentrations
著者:: Sally Demirdjian, 等
出版事項: (2025-01-01)
著者:: Sally Demirdjian, 等
出版事項: (2025-01-01)
The effect of a treatment switch to integrase Strand transfer inhibitor–based regimens on weight gain and other metabolic syndrome-related conditions
著者:: Omer Maman, 等
出版事項: (2024-02-01)
著者:: Omer Maman, 等
出版事項: (2024-02-01)
Bictegravir/Emtricitabine/Tenofovir Alafenamide for HIV-1: What is the Hidden Potential of This Emerging Treatment?
著者:: Januszka JE, 等
出版事項: (2023-11-01)
著者:: Januszka JE, 等
出版事項: (2023-11-01)
The differential effects of integrase strand transfer inhibitors and efavirenz on neuropsychiatric conditions and brain imaging in HIV-positive men who have sex with men
著者:: Yihui He, 等
出版事項: (2024-08-01)
著者:: Yihui He, 等
出版事項: (2024-08-01)
A Practical Approach to Bicyclic Carbamoyl Pyridones with Application to the Synthesis of HIV-1 Integrase Strand Transfer Inhibitors
著者:: Pankaj S. Mahajan, 等
出版事項: (2023-02-01)
著者:: Pankaj S. Mahajan, 等
出版事項: (2023-02-01)
Drug resistance profiles in patients attending to an HIV clinic in Quito: a pilot study
著者:: Paulina Quirola Amores, 等
出版事項: (2025-07-01)
著者:: Paulina Quirola Amores, 等
出版事項: (2025-07-01)
Applying Next-Generation Sequencing to Track HIV-1 Drug Resistance Mutations Circulating in Portugal
著者:: Victor Pimentel, 等
出版事項: (2024-04-01)
著者:: Victor Pimentel, 等
出版事項: (2024-04-01)
New onset type 2 diabetes mellitus risks with integrase strand transfer inhibitors-based regimens: A systematic review and meta-analysis
著者:: Violet Dismas Kajogoo, 等
出版事項: (2023-03-01)
著者:: Violet Dismas Kajogoo, 等
出版事項: (2023-03-01)
Exploring the interplay between antiretroviral therapy and the gut-oral microbiome axis in people living with HIV
著者:: Aswathy Narayanan, 等
出版事項: (2024-08-01)
著者:: Aswathy Narayanan, 等
出版事項: (2024-08-01)
Causes of HIV Treatment Interruption during the Last 20 Years: A Multi-Cohort Real-Life Study
著者:: Andrea De Vito, 等
出版事項: (2023-03-01)
著者:: Andrea De Vito, 等
出版事項: (2023-03-01)
A Pharmacokinetic Dose-Optimization Study of Cabotegravir and Bictegravir in a Mouse Pregnancy Model
著者:: Haneesha Mohan, 等
出版事項: (2022-08-01)
著者:: Haneesha Mohan, 等
出版事項: (2022-08-01)
Low-level viraemia despite emergence of dolutegravir-resistant variants
著者:: Johannes C. Botha, 等
出版事項: (2022-09-01)
著者:: Johannes C. Botha, 等
出版事項: (2022-09-01)
Elucidating the Molecular Determinants of the Binding Modes of a Third-Generation HIV-1 Integrase Strand Transfer Inhibitor: The Importance of Side Chain and Solvent Reorganization
著者:: Qinfang Sun, 等
出版事項: (2024-01-01)
著者:: Qinfang Sun, 等
出版事項: (2024-01-01)
Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome in initiating ART among HIV-Infected patients in China-risk factors and management
著者:: Honghong Yang, 等
出版事項: (2024-01-01)
著者:: Honghong Yang, 等
出版事項: (2024-01-01)
Safety and efficacy of pharmacotherapy containing INSTIs and chemotherapy drugs in people living with HIV and concomitant colorectal cancer
著者:: Jing Yang, 等
出版事項: (2022-09-01)
著者:: Jing Yang, 等
出版事項: (2022-09-01)
Effect of dolutegravir-based antiretroviral therapy on glycemic control in female mice
著者:: Valeriya Dontsova, 等
出版事項: (2025-06-01)
著者:: Valeriya Dontsova, 等
出版事項: (2025-06-01)
HIV Infection, Antiretroviral Drugs, and the Vascular Endothelium
著者:: Georgette D. Kanmogne
出版事項: (2024-04-01)
著者:: Georgette D. Kanmogne
出版事項: (2024-04-01)
Historiografía sobre las significaciones imaginarias de infancia en la cultura de Occidente
著者:: Cecilia Rincón Verdugo
出版事項: (2018-01-01)
著者:: Cecilia Rincón Verdugo
出版事項: (2018-01-01)
Comparison of Integrase Strand Transfer Inhibitors (INSTIs) and Protease-Boosted Inhibitors (PIs) on the Reduction in Chronic Immune Activation in a Virally Suppressed, Mainly Male Population Living with HIV (PLWH)
著者:: Thomas Nitsotolis, 等
出版事項: (2024-02-01)
著者:: Thomas Nitsotolis, 等
出版事項: (2024-02-01)
Prevalence and Associated Factors for HPV in People Living with HIV: Are INSTIs Protective Against HPV-16? The GAIA Study
著者:: Omar Hernández-López, 等
出版事項: (2025-08-01)
著者:: Omar Hernández-López, 等
出版事項: (2025-08-01)
Persistent cell-associated HIV-1 RNA in virally suppressed individuals on INSTI-based ART
著者:: Kazuo Suzuki, 等
出版事項: (2025-12-01)
著者:: Kazuo Suzuki, 等
出版事項: (2025-12-01)
Folate deficiency increases the incidence of dolutegravir-associated foetal defects in a mouse pregnancy modelResearch in context
著者:: Haneesha Mohan, 等
出版事項: (2023-09-01)
著者:: Haneesha Mohan, 等
出版事項: (2023-09-01)
Evaluation of HIV-1 integrase resistance emergence and evolution in patients treated with integrase inhibitors
著者:: Rossana Scutari, 等
出版事項: (2020-03-01)
著者:: Rossana Scutari, 等
出版事項: (2020-03-01)
Maternal HIV Infection and Antiretroviral Therapy in Pregnancy: Implications for Vertical Transmission, Fetal Safety, and Long-Term Infant Outcomes
著者:: Tudor Fleșeriu, 等
出版事項: (2025-08-01)
著者:: Tudor Fleșeriu, 等
出版事項: (2025-08-01)
Comparative Analyses of Antiviral Potencies of Second-Generation Integrase Strand Transfer Inhibitors (INSTIs) and the Developmental Compound 4d Against a Panel of Integrase Quadruple Mutants
著者:: Steven J. Smith, 等
出版事項: (2025-01-01)
著者:: Steven J. Smith, 等
出版事項: (2025-01-01)
Institucionalni okvir glasbenih dejavnosti v Sarajevu v obdobju med obema vojnama
著者:: Fatima Hadžić
出版事項: (2013-06-01)
著者:: Fatima Hadžić
出版事項: (2013-06-01)
Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis
著者:: Jennifer L Elliott, 等
出版事項: (2020-09-01)
著者:: Jennifer L Elliott, 等
出版事項: (2020-09-01)
Multimodal Functionalities of HIV-1 Integrase
著者:: Alan N. Engelman, 等
出版事項: (2022-04-01)
著者:: Alan N. Engelman, 等
出版事項: (2022-04-01)
First report of computational protein–ligand docking to evaluate susceptibility to HIV integrase inhibitors in HIV-infected Iranian patients
著者:: Farzane Ghasabi, 等
出版事項: (2022-07-01)
著者:: Farzane Ghasabi, 等
出版事項: (2022-07-01)
類似資料
-
First Reported Case of Integrase Strand Transfer Inhibitor Resistance in Suriname: Unusual Drug Resistance Mutations Following Exposure to Dolutegravir
著者:: Rachel C. Sno, 等
出版事項: (2025-02-01) -
Genetic Features of HIV-1 Integrase Sub-Subtype A6 Predominant in Russia and Predicted Susceptibility to INSTIs
著者:: Alina Kirichenko, 等
出版事項: (2020-07-01) -
A clinical review of HIV integrase strand transfer inhibitors (INSTIs) for the prevention and treatment of HIV-1 infection
著者:: Alexa Vyain Zhao, 等
出版事項: (2022-10-01) -
Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs
著者:: Steven J. Smith, 等
出版事項: (2021-01-01) -
Changes in central adipose tissue after switching to integrase inhibitors
著者:: Paula Debroy, 等
出版事項: (2020-11-01)
