Assessing the adaptive role of cannabidivarinic acid (CBDVA) in aphid defense in Cannabis sativa

Abstract Background Cannabis sativa has unique secondary metabolites known as cannabinoids, which include tetrahydrocannabinol (THC) and cannabidiol (CBD) and more than 100 related secondary metabolites. There is increasing evidence that cannabinoids can affect insect fecundity and survival. In this...

Full description

Bibliographic Details
Published in:	Journal of Cannabis Research
Main Authors:	Jacob MacWilliams, Venkatesh Padimi, Olivia Carter, Korey Brownstein, Zachary Stansell, Tyler Gordon, Punya Nachappa
Format:	Article
Language:	English
Published:	BMC 2025-06-01
Subjects:	Hemp Cannabis aphids Green peach aphids Cannabinoids CBD Pest management
Online Access:	https://doi.org/10.1186/s42238-025-00291-x

Similar Items

Assessing the adaptive role of cannabidiol (CBD) in Cannabis sativa defense against cannabis aphids
by: Jacob MacWilliams, et al.
Published: (2023-10-01)

Evaluating Growth, Biomass and Cannabinoid Profiles of Floral Hemp Varieties under Different Planting Dates in Organic Soils of Florida
by: Saroop S. Sandhu, et al.
Published: (2022-11-01)

The Effect of Transplant Date and Plant Spacing on Biomass Production for Floral Hemp (<i>Cannabis sativa</i> L.)
by: Eric R. Linder, et al.
Published: (2022-08-01)

Genistein and Aphid Probing Behavior: Case Studies on Polyphagous Aphid Species
by: Anna Wróblewska-Kurdyk, et al.
Published: (2024-12-01)

Quercetin and Rutin as Modifiers of Aphid Probing Behavior
by: Katarzyna Stec, et al.
Published: (2021-06-01)

The <i>foraging</i> Gene Is Involved in the Presence of Wings and Explorative Behaviours in Parthenogenetic Females of the Aphid <i>Myzus persicae</i>
by: Mauro Mandrioli, et al.
Published: (2022-03-01)

Opportunities, Challenges, and Scientific Progress in Hemp Crops
by: Kacper Piotr Kaminski, et al.
Published: (2024-05-01)

Composition of fatty acids in hemp leaves (Cannabis sativa L.) under the impact of aphids and a herbicide
by: Roma Durak, et al.
Published: (2025-07-01)

Aphid resistance in potato
by: E. E. Radchenko
Published: (2017-03-01)

The Effect of Harvest Date on Temporal Cannabinoid and Biomass Production in the Floral Hemp (<i>Cannabis sativa</i> L.) Cultivars BaOx and Cherry Wine
by: Eric R. Linder, et al.
Published: (2022-10-01)

Study on knowledge and perceptions on the uptake of non-medicinal cannabis-substances and preparations by Portuguese consumers: Borderline issues
by: Alexandre Elias, et al.
Published: (2024-12-01)

Differentiating Cannabis Products: Drugs, Food, and Supplements
by: Arash Salehi, et al.
Published: (2022-06-01)

Application of four molecular markers for breeding peach aphid (Myzus persicae Sülzer) resistance
by: CHEN Xuejia, et al.
Published: (2025-07-01)

Aphids (Homoptera, Aphidodea) inhabiting the trees Crataegus x media Bechst. in the urban green area. Part II. Domination and frequency of aphids, their enemies and the damage caused by aphids
by: Aneta Sławińska, et al.
Published: (2013-12-01)

Hemp (Cannabis sativa L.) research priorities: Opinions from United States hemp stakeholders
by: Shelby Ellison
Published: (2021-04-01)

Chemical Characterization of 29 Industrial Hempseed (<i>Cannabis sativa</i> L.) Varieties
by: Sheyla Arango, et al.
Published: (2024-01-01)

Cannabis and the Anxiety of Fragmentation—A Systems Approach for Finding an Anxiolytic Cannabis Chemotype
by: Brishna S. Kamal, et al.
Published: (2018-10-01)

Indications and administration practices amongst medical cannabis healthcare providers: a cross-sectional survey
by: Jamie Corroon, et al.
Published: (2019-12-01)

Analysis of Twenty Years of Suction Trap Data on the Flight Activity of <i>Myzus persicae</i> and <i>Brevicoryne brassicae</i>, Two Main Vectors of Oilseed Rape Infection Viruses
by: Lucie Slavíková, et al.
Published: (2024-08-01)

Antifeedant Potential of Geranylacetone and Nerylacetone and Their Epoxy-Derivatives against <i>Myzus persicae</i> (Sulz.)
by: Anna Wróblewska-Kurdyk, et al.
Published: (2022-12-01)

Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort
by: Eric P. Baron, et al.
Published: (2018-05-01)

Evaluation of the Susceptibility of Some Eggplant Cultivars to Green Peach Aphid, <i>Myzus persicae</i> (Sulzer) (Hemiptera: Aphididae)
by: Zienab Raeyat, et al.
Published: (2021-01-01)

Cannabis, a cause for anxiety? A critical appraisal of the anxiogenic and anxiolytic properties
by: Lara Sharpe, et al.
Published: (2020-10-01)

Impact of N, P, K, and Humic Acid Supplementation on the Chemical Profile of Medical Cannabis (Cannabis sativa L)
by: Nirit Bernstein, et al.
Published: (2019-06-01)

Dual Biocontrol Potential of the Entomopathogenic Fungus, Isaria javanica, for Both Aphids and Plant Fungal Pathogens
by: Beom Ryong Kang, et al.
Published: (2018-10-01)

The Known and Unknowns of Aphid Biotypes, and Their Role in Mediating Host Plant Defenses
by: Neetu Khanal, et al.
Published: (2023-01-01)

Industrial Hemp (<i>Cannabis sativa</i> subsp. <i>sativa</i>) as an Emerging Source for Value-Added Functional Food Ingredients and Nutraceuticals
by: H. P. Vasantha Rupasinghe, et al.
Published: (2020-09-01)

Probing behavior of Aphis fabae and Myzus persicae on three species of grapevines with analysis of grapevine leaf anatomy and allelochemicals
by: M. Paprocka, et al.
Published: (2023-07-01)

Use of Medicinal Cannabis and Synthetic Cannabinoids in Post-Traumatic Stress Disorder (PTSD): A Systematic Review
by: Laura Orsolini, et al.
Published: (2019-08-01)

Immune Responses Are Differentially Regulated by Root, Stem, Leaf, and Flower Extracts of Female and Male CBD Hemp (<i>Cannabis sativa</i> L.) Plants
by: Laura G. A. Esposito, et al.
Published: (2021-10-01)

Legal <i>Cannabis sativa</i> L. Dried Inflorescences: Cannabinoids Content and Cytotoxic Activity against Human HepG2 Cell Line
by: Maria Assunta Acquavia, et al.
Published: (2023-04-01)

Biological Activity of <i>Cannabis sativa</i> L. Extracts Critically Depends on Solvent Polarity and Decarboxylation
by: Guillermo Moreno-Sanz, et al.
Published: (2020-10-01)

A One-Step Grafting Methodology Can Adjust Stem Morphology and Increase THCA Yield in Medicinal Cannabis
by: Sarah Jane Purdy, et al.
Published: (2022-03-01)

A comparative phytocannabinoid profiling of resin from five hemp (Cannabis sativa L.) cultivars from central-northern Morocco
by: Ismail El Bakali, et al.
Published: (2025-09-01)

Plant Viruses Can Alter Aphid-Triggered Calcium Elevations in Infected Leaves
by: Christiane Then, et al.
Published: (2021-12-01)

Podocarpus Aphid (suggested common name) Neophyllaphis podocarpi Takahashi (Insecta: Hemiptera: Aphididae)
by: Eleanor F. Phillips, et al.
Published: (2017-12-01)

Medical Cannabis in Pediatric Oncology: Friend or Foe?
by: Megan Malach, et al.
Published: (2022-03-01)

Entomopathogenic Fungi Effectively Control <i>Phorodon cannabis</i> Aphid Population in <i>Cannabis sativa</i> Plants
by: Daniel Lopez Restrepo, et al.
Published: (2025-03-01)

Impact of Phosphorus on <i>Cannabis sativa</i> Reproduction, Cannabinoids, and Terpenes
by: Paul Cockson, et al.
Published: (2020-11-01)

Therapeutic Potential of Cannabis: A Comprehensive Review of Current and Future Applications
by: Zach J. Leinen, et al.
Published: (2023-09-01)