Amoebic Liver Abscess: Potential Application of New Diagnostic Techniques for an Old Pathogen

Abstract Amoebic liver abscess is a severe and potentially life-threatening infection requiring prompt diagnosis and early targeted treatment. Diagnosis is challenging because conventional diagnostic methods such as light microscopy and serology are often unreliable. Molecular techniques have emerge...

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Bibliographic Details
Published in:Infectious Diseases and Therapy
Main Authors: Federica Portunato, Claudia Bartalucci, Antonio Vena, Daniele Roberto Giacobbe, Elisa Porcile, Paolo Montanelli, Nataniele Piol, Monica Centanaro, Enzo Andorno, Matteo Bassetti
Format: Article
Language:English
Published: Adis, Springer Healthcare 2024-03-01
Subjects:
Amoebiasis
Liver abscess
FilmArray gastrointestinal panel
Online Access:https://doi.org/10.1007/s40121-024-00934-1
Description
Summary:Abstract Amoebic liver abscess is a severe and potentially life-threatening infection requiring prompt diagnosis and early targeted treatment. Diagnosis is challenging because conventional diagnostic methods such as light microscopy and serology are often unreliable. Molecular techniques have emerged as an additional diagnostic tool, suddenly becoming the new diagnostic reference standard. More recently, commercial multiplex PCR panels, including FilmArray, have been introduced, which permit the simultaneous detection of several enteric pathogens including Entamoeba histolytica in stool samples. We report a case of an amoebic liver abscess promptly diagnosed by FilmArray gastrointestinal panel performed on liver drainage fluid.
ISSN:2193-8229
2193-6382

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